8AU4

Structural insights reveal a heterotetramer between oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator

Summary for 8AU4

• Entry DOI: 10.2210/pdb8au4/pdb
• NMR Information: BMRB: 34754
• Descriptor: Ral guanine nucleotide dissociation stimulator-like 2 (1 entity in total)
• Functional Keywords: small gtpase ras signalling protein-protein interaction nmr x-ray crystallography, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 10972.41

Authors

Tariq, M.,Ikeya, T.,Togashi, N.,Fairall, L.,Alejo, C.B.,Kamei, S.,Alonso, B.R.,Campillo, M.A.M.,Hudson, A.,Ito, Y.,Schwabe, J.,Dominguez, C.,Tanaka, K. (deposition date: 2022-08-25, release date: 2023-08-23, Last modification date: 2023-10-25)

• Primary citation: Tariq, M.,Ikeya, T.,Togashi, N.,Fairall, L.,Kamei, S.,Mayooramurugan, S.,Abbott, L.R.,Hasan, A.,Bueno-Alejo, C.,Sukegawa, S.,Romartinez-Alonso, B.,Muro Campillo, M.A.,Hudson, A.J.,Ito, Y.,Schwabe, J.W.,Dominguez, C.,Tanaka, K.; Structural insights into the complex of oncogenic KRas4B G12V and Rgl2, a RalA/B activator.; Life Sci Alliance, 7:-, 2024; PubMed: 37833074; DOI: 10.26508/lsa.202302080

Experimental method

SOLUTION NMR