8B69

Heterotetramer of K-Ras4B(G12V) and Rgl2(RBD)

Summary for 8B69

Entry DOI	10.2210/pdb8b69/pdb
Related	8AU4
Descriptor	Ral guanine nucleotide dissociation stimulator-like 2, Isoform 2B of GTPase KRas, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	kras, ralgef, rgl2, ral pathway, ras signalling, small g-protein, ras binding domain, oncoprotein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	61839.65
Authors	Tariq, M.,Fairall, L.,Romartinez-Alonso, B.,Dominguez, C.,Schwabe, J.W.R.,Tanaka, K. (deposition date: 2022-09-26, release date: 2023-08-23, Last modification date: 2023-10-25)
Primary citation	Tariq, M.,Ikeya, T.,Togashi, N.,Fairall, L.,Kamei, S.,Mayooramurugan, S.,Abbott, L.R.,Hasan, A.,Bueno-Alejo, C.,Sukegawa, S.,Romartinez-Alonso, B.,Muro Campillo, M.A.,Hudson, A.J.,Ito, Y.,Schwabe, J.W.,Dominguez, C.,Tanaka, K. Structural insights into the complex of oncogenic KRas4B G12V and Rgl2, a RalA/B activator. Life Sci Alliance, 7:-, 2024 Cited by PubMed: 37833074 DOI: 10.26508/lsa.202302080 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.07 Å)

Structure validation