8AU4
Structural insights reveal a heterotetramer between oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator
Summary for 8AU4
Entry DOI | 10.2210/pdb8au4/pdb |
NMR Information | BMRB: 34754 |
Descriptor | Ral guanine nucleotide dissociation stimulator-like 2 (1 entity in total) |
Functional Keywords | small gtpase ras signalling protein-protein interaction nmr x-ray crystallography, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 10972.41 |
Authors | Tariq, M.,Ikeya, T.,Togashi, N.,Fairall, L.,Alejo, C.B.,Kamei, S.,Alonso, B.R.,Campillo, M.A.M.,Hudson, A.,Ito, Y.,Schwabe, J.,Dominguez, C.,Tanaka, K. (deposition date: 2022-08-25, release date: 2023-08-23, Last modification date: 2023-10-25) |
Primary citation | Tariq, M.,Ikeya, T.,Togashi, N.,Fairall, L.,Kamei, S.,Mayooramurugan, S.,Abbott, L.R.,Hasan, A.,Bueno-Alejo, C.,Sukegawa, S.,Romartinez-Alonso, B.,Muro Campillo, M.A.,Hudson, A.J.,Ito, Y.,Schwabe, J.W.,Dominguez, C.,Tanaka, K. Structural insights into the complex of oncogenic KRas4B G12V and Rgl2, a RalA/B activator. Life Sci Alliance, 7:-, 2024 Cited by PubMed: 37833074DOI: 10.26508/lsa.202302080 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report