1BYC
| CRYSTAL STRUCTURES OF SOYBEAN BETA-AMYLASE REACTED WITH BETA-MALTOSE AND MALTAL: ACTIVE SITE COMPONENTS AND THEIR APPARENT ROLE IN CATALYSIS | 分子名称: | BETA-AMYLASE, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Mikami, B, Degano, M, Hehre, E.J, Sacchettini, J.C. | 登録日 | 1994-01-25 | 公開日 | 1994-07-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of soybean beta-amylase reacted with beta-maltose and maltal: active site components and their apparent roles in catalysis. Biochemistry, 33, 1994
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1BYD
| CRYSTAL STRUCTURES OF SOYBEAN BETA-AMYLASE REACTED WITH BETA-MALTOSE AND MALTAL: ACTIVE SITE COMPONENTS AND THEIR APPARENT ROLE IN CATALYSIS | 分子名称: | BETA-AMYLASE, SULFATE ION, alpha-D-glucopyranose-(1-4)-2-deoxy-beta-D-arabino-hexopyranose | 著者 | Mikami, B, Degano, M, Hehre, E.J, Sacchettini, J.C. | 登録日 | 1994-01-25 | 公開日 | 1994-07-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of soybean beta-amylase reacted with beta-maltose and maltal: active site components and their apparent roles in catalysis. Biochemistry, 33, 1994
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7BR0
| Crystal structure of AclR, a thioredoxin oxidoreductase fold protein carrying the CXXH catalytic motif | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Pyr_redox_2 domain-containing protein | 著者 | Hara, K, Hashimoto, H, Maeda, N, Watanabe, K, Hertweck, C, Tsunematsu, Y. | 登録日 | 2020-03-26 | 公開日 | 2020-12-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Specialized Flavoprotein Promotes Sulfur Migration and Spiroaminal Formation in Aspirochlorine Biosynthesis. J.Am.Chem.Soc., 143, 2021
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1IQQ
| Crystal Structure of Japanese pear S3-RNase | 分子名称: | S3-RNase, beta-D-xylopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Matsuura, T, Sakai, H, Norioka, S. | 登録日 | 2001-07-25 | 公開日 | 2001-11-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure at 1.5-A resolution of Pyrus pyrifolia pistil ribonuclease responsible for gametophytic self-incompatibility. J.Biol.Chem., 276, 2001
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6L4Q
| Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Clado-B | 分子名称: | (3R)-3-[[(3R)-3-methylpiperidin-1-yl]methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one, LYSINE, Lysine--tRNA ligase | 著者 | Babbar, P, Sharma, A, Manickam, Y, Mishra, S, Harlos, K. | 登録日 | 2019-10-19 | 公開日 | 2021-05-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin inhibitor, Cla-B Chembiochem, 2021
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6L3Y
| Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Clado-C | 分子名称: | (3R)-3-[[(3S)-3-ethylpiperidin-1-yl]methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one, LYSINE, Lysine--tRNA ligase, ... | 著者 | Babbar, P, Sharma, A, Mishra, S, Manickam, Y, Harlos, K. | 登録日 | 2019-10-15 | 公開日 | 2021-05-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin inhibitor, Cla-B Chembiochem, 2021
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6G3B
| AvaII restriction endonuclease in complex with an RNA/DNA hybrid | 分子名称: | DNA (5'-D(*CP*CP*AP*TP*GP*GP*TP*CP*CP*TP*A)-3'), RNA (5'-R(P*GP*UP*AP*GP*GP*AP*CP*CP*AP*UP*G)-3'), Type II site-specific deoxyribonuclease | 著者 | Kisiala, M, Kowalska, M, Czapinska, H, Bochtler, M. | 登録日 | 2018-03-24 | 公開日 | 2019-04-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Restriction endonucleases that cleave RNA/DNA heteroduplexes bind dsDNA in A-like conformation Nucleic Acids Res., 2020
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1WFS
| Solution Structure of Glia Maturation Factor-gamma from Mus Musculus | 分子名称: | Glia maturation factor gamma | 著者 | Goroncy, A.K, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-05-26 | 公開日 | 2004-11-26 | 最終更新日 | 2022-12-21 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structures of actin depolymerizing factor homology domains. Protein Sci., 18, 2009
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5YFI
| Crystal structure of the anti-human prostaglandin E receptor EP4 antibody Fab fragment | 分子名称: | Heavy chain of Fab fragment, Light chain of Fab fragment, ZINC ION | 著者 | Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T. | 登録日 | 2017-09-21 | 公開日 | 2018-12-05 | 最終更新日 | 2019-03-06 | 実験手法 | X-RAY DIFFRACTION (1.848 Å) | 主引用文献 | Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface. Nat. Chem. Biol., 15, 2019
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5YHL
| Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and an antagonist Br-derivative | 分子名称: | 4-[2-[[(2R)-2-(4-bromanylnaphthalen-1-yl)propanoyl]amino]-4-cyano-phenyl]butanoic acid, Heavy chain of Fab fragment, Light chain of Fab fragment, ... | 著者 | Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T. | 登録日 | 2017-09-28 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface. Nat. Chem. Biol., 15, 2019
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5YWY
| Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and ONO-AE3-208 | 分子名称: | 4-[4-cyano-2-[[(2R)-2-(4-fluoranylnaphthalen-1-yl)propanoyl]amino]phenyl]butanoic acid, Heavy chain of Fab fragment, Light chain of Fab fragment, ... | 著者 | Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T. | 登録日 | 2017-11-30 | 公開日 | 2018-12-05 | 最終更新日 | 2018-12-19 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface. Nat. Chem. Biol., 15, 2019
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5Y25
| EGFR kinase domain mutant (T790M/L858R) with covalent ligand NS-062 | 分子名称: | (2R)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamide, Epidermal growth factor receptor | 著者 | Shiroishi, M, Abe, Y, Caaveiro, J.M.M, Sakamoto, S, Morimoto, S, Fuchida, H, Shindo, N, Ojida, A. | 登録日 | 2017-07-24 | 公開日 | 2018-07-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.102 Å) | 主引用文献 | Selective and reversible modification of kinase cysteines with chlorofluoroacetamides. Nat.Chem.Biol., 15, 2019
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2LC2
| Solution structure of the RXLR effector P. capsici AVR3a4 | 分子名称: | AVR3a4 | 著者 | Li, H, Koshiba, S, Yaeno, T, Sato, M, Watanabe, S, Harada, T, Shirasu, K, Kigawa, T. | 登録日 | 2011-04-12 | 公開日 | 2011-08-03 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | A PIP-binding interface in the oomycete RXLR effector AVR3A is required for its accumulation in host cells to modulate plant immunity To be Published
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1GCU
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6A88
| Crystal Structure of T. gondii prolyl tRNA synthetase with Febrifugine and ATP Analog | 分子名称: | 3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Kumari, S, Mishra, S, Yogavel, M, Sharma, A. | 登録日 | 2018-07-06 | 公開日 | 2019-10-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | 主引用文献 | Conformational heterogeneity in apo and drug-bound structures of Toxoplasma gondii prolyl-tRNA synthetase. Acta Crystallogr.,Sect.F, 75, 2019
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6AA0
| Crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in Apo Form | 分子名称: | GLYCEROL, Prolyl-tRNA synthetase (ProRS) | 著者 | Mishra, S, Kumari, S, Sharma, A, Yogavel, M. | 登録日 | 2018-07-16 | 公開日 | 2019-10-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Conformational heterogeneity in apo and drug-bound structures of Toxoplasma gondii prolyl-tRNA synthetase. Acta Crystallogr.,Sect.F, 75, 2019
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3UG2
| Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in complex with gefitinib | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, Gefitinib | 著者 | Parker, L.J, Handa, N, Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | 登録日 | 2011-11-02 | 公開日 | 2012-03-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor Oncogene, 32, 2013
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3UG1
| Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in the apo form | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor | 著者 | Parker, L.J, Handa, N, Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | 登録日 | 2011-11-02 | 公開日 | 2012-03-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor Oncogene, 32, 2013
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3VJN
| Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in complex with AMPPNP. | 分子名称: | Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Semba, K, Yamamoto, T, Yokoyama, S. | 登録日 | 2011-10-27 | 公開日 | 2012-03-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor. Oncogene, 32, 2013
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3VJO
| Crystal structure of the wild-type EGFR kinase domain in complex with AMPPNP. | 分子名称: | Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Semba, K, Yamamoto, T, Yokoyama, S. | 登録日 | 2011-10-27 | 公開日 | 2012-03-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor. Oncogene, 32, 2013
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6IOY
| Crystal structure of Porphyromonas gingivalis acetate kinase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Acetate kinase, SULFATE ION | 著者 | Kezuka, Y, Yoshida, Y, Nonaka, T. | 登録日 | 2018-10-31 | 公開日 | 2019-04-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Characterization of the phosphotransacetylase-acetate kinase pathway for ATP production inPorphyromonas gingivalis. J Oral Microbiol, 11, 2019
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6IOX
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6INZ
| Crystal structure of solute-binding protein complexed with unsaturated hyaluronan disaccharide | 分子名称: | 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Extracellular solute-binding protein family 1, ... | 著者 | Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | 登録日 | 2018-10-29 | 公開日 | 2019-09-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.289 Å) | 主引用文献 | Substrate recognition by bacterial solute-binding protein is responsible for import of extracellular hyaluronan and chondroitin sulfate from the animal host. Biosci.Biotechnol.Biochem., 83, 2019
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6IOW
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6KCS
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