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6VPX
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BU of 6vpx by Molmil
Nanodisc of full-length HIV-1 Envelope glycoprotein clone AMC011 in complex with one PGT151 Fab and three 10E8 Fabs
Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rantalainen, K, Ward, A.B.W.
Deposit date:2020-02-04
Release date:2020-04-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5 Å)
Cite:HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies.
Cell Rep, 31, 2020
6DCQ
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BU of 6dcq by Molmil
Ectodomain of full length, wild type HIV-1 glycoprotein clone PC64M18C043 in complex with PGT151 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rantalainen, K.
Deposit date:2018-05-08
Release date:2018-06-27
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6OLP
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BU of 6olp by Molmil
Full length HIV-1 Env AMC011 in complex with PGT151 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rantalainen, K, Cottrell, C.A.
Deposit date:2019-04-16
Release date:2019-07-31
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics.
Plos Pathog., 15, 2019
6NIJ
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BU of 6nij by Molmil
PGT145 Fab in complex with full length AMC011 HIV-1 Env
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 Glycoprotein 120, ...
Authors:Cottrell, C.A, Torrents de la Pena, A, Rantalainen, K, Torres, J.L, Ward, A.B.
Deposit date:2018-12-29
Release date:2019-07-31
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics.
Plos Pathog., 15, 2019
7L89
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BU of 7l89 by Molmil
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-4 from animal Rh.32034 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Rantalainen, K, Perrett, H.R, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8U
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BU of 7l8u by Molmil
BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-2 from animal Rh.33311 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Rantalainen, K, Ward, A.B.
Deposit date:2021-01-01
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8G
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BU of 7l8g by Molmil
BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-3 from animal Rh.33172 (Wk38 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Antanasijevic, A, Sewall, L.M, Rantalainen, K, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-09-08
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
6CA9
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BU of 6ca9 by Molmil
Crystal structure of Fab PCT64_LMCA (SAR), the least mutated common ancestor of the HIV-1 broadly neutralizing antibody lineage PCT64
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, PCT64_LMCA Fab heavy chain, ...
Authors:Omorodion, O, Wilson, I.A.
Deposit date:2018-01-29
Release date:2018-06-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6CA7
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BU of 6ca7 by Molmil
Crystal structure of PCT64_13C, a strain specific anti-HIV antibody
Descriptor: PCT64_13C heavy chain, PCT64_13C light chain
Authors:Murrell, S, Wilson, I.A.
Deposit date:2018-01-29
Release date:2018-06-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.643 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6CA6
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BU of 6ca6 by Molmil
Crystal structure of PCT64_35S, a broadly neutralizing anti-HIV antibody.
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, PCT64_35S heavy chain, ...
Authors:Murrell, S, Wilson, I.A.
Deposit date:2018-01-29
Release date:2018-06-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
8E1P
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BU of 8e1p by Molmil
Crystal structure of BG505 SOSIP.v4.1-GT1.2 trimer in complex with gl-PGV20 and PGT124 Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIP.v4.1-GT1.2gp120, ...
Authors:Sarkar, A, Kumar, S, Wilson, I.A.
Deposit date:2022-08-11
Release date:2023-06-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.82 Å)
Cite:Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.
Cell Rep Med, 4, 2023
6IEQ
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BU of 6ieq by Molmil
Crystal Structure of HIV-1 Env ConM SOSIP.v7 in Complex with bNAb PGT124 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab Heavy Chain, ...
Authors:Han, B.W, Wilson, I.A.
Deposit date:2018-09-16
Release date:2019-05-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence.
Nat Commun, 10, 2019
5FEH
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BU of 5feh by Molmil
Crystal structure of PCT64_35B, a broadly neutralizing anti-HIV antibody
Descriptor: 1,2-ETHANEDIOL, PCT64_26 Fab heavy chain, PCT64_26 Fab light chain, ...
Authors:Murrell, S, Wilson, I.A.
Deposit date:2015-12-17
Release date:2017-08-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage.
Immunity, 47, 2017
8GJE
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BU of 8gje by Molmil
HIV-1 Env subtype C CZA97.12 SOSIP.664 in complex with 3BNC117 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 Fab heavy chain, ...
Authors:Ozorowski, G, Lee, J.H, Ward, A.B.
Deposit date:2023-03-15
Release date:2023-10-18
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.
Plos Pathog., 19, 2023
6MAR
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BU of 6mar by Molmil
HIV-1 Envelope Glycoprotein Clone BG505 delCT N332T in complex with broadly neutralizing antibody Fab PGT151
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2018-08-28
Release date:2018-09-26
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer.
Nat Commun, 9, 2018
8SX3
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BU of 8sx3 by Molmil
10E8-GT10.2 immunogen in complex with human Fab 10E8 and mouse Fab W6-10
Descriptor: 10E8 Fab heavy chain, 10E8 light chain, 10E8-GT10.2 immunogen, ...
Authors:Huang, J, Ozorowski, G, Ward, A.B.
Deposit date:2023-05-19
Release date:2024-05-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8U03
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BU of 8u03 by Molmil
Crystal structure of non-glycosylated 10E8-GT10.1 scaffold in complex with a human 10E8 NGS precursor (10E8-NGS-03)
Descriptor: 10E8-GT10.1 epitope scaffold, 10E8-NGS-03 Fab Light Chain, 10E8-NGS-03 Fab heavy chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2023-08-28
Release date:2024-06-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8TZW
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BU of 8tzw by Molmil
Crystal structure of 10E8-GT4 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
Descriptor: 10E8-GT4 epitope scaffold, 10E8-IGL1 Fab Light Chain, 10E8-IGL1 Fab heavy chain
Authors:Irimia, A, Wilson, I.A.
Deposit date:2023-08-28
Release date:2024-06-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8TZN
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BU of 8tzn by Molmil
Crystal structure of 10E8-GT10.2 HIV-1 MPER scaffold in complex with a non-human primate W3-01 Fab
Descriptor: 10E8-GT10.2 MPER scaffold, W3-01 Fab Heavy Chain, W3-01 Fab Light Chain
Authors:Lee, C.C.D, Wilson, I.A.
Deposit date:2023-08-27
Release date:2024-06-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8U08
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BU of 8u08 by Molmil
Crystal structure of 10E8-GT11 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
Descriptor: 10E8-GT11 epitope scaffold, 10E8-IGL1 heavy chain, 10E8-IGL1 light chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2023-08-28
Release date:2024-06-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8V2E
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BU of 8v2e by Molmil
Crystal structure of B055 scaffold boost immunogen in complex with a mature 10E8 Fab
Descriptor: 10E8 EPITOPE SCAFFOLD B055, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 10E8 FAB HEAVY CHAIN, ...
Authors:Cho, S.Y, Wilson, I.A.
Deposit date:2023-11-22
Release date:2024-06-12
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
6O3G
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BU of 6o3g by Molmil
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41).
Descriptor: GLYCEROL, MEPER peptide, region 671-683 of HIV-1 gp41, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2019-02-26
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.645 Å)
Cite:An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6O3K
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BU of 6o3k by Molmil
Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3
Descriptor: GLYCEROL, PGZL1.H4K3 heavy chain, PGZL1.H4K3 light chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2019-02-26
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6O3U
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BU of 6o3u by Molmil
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with 06:0 PA
Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, GLYCEROL, PGZL1.H4K3 heavy chain, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2019-02-27
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.105 Å)
Cite:An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6O3D
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BU of 6o3d by Molmil
Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.
Descriptor: GLYCEROL, PGZL1 FAB HEAVY CHAIN, PGZL1 FAB LIGHT CHAIN, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2019-02-26
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019

 

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