6O3U
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with 06:0 PA
Summary for 6O3U
Entry DOI | 10.2210/pdb6o3u/pdb |
Related | 6O3D 6O3G 6O3J 6O3K 6O3L 6O41 6O42 |
Descriptor | PGZL1.H4K3 light chain, PGZL1.H4K3 heavy chain, GLYCEROL, ... (6 entities in total) |
Functional Keywords | pgzl1.h4k3 anti hiv-1, gp41 mper, membrane lipids, broadly neutralising hiv-1 antibody, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 8 |
Total formula weight | 195200.62 |
Authors | Irimia, A.,Wilson, I.A. (deposition date: 2019-02-27, release date: 2019-12-04, Last modification date: 2023-10-11) |
Primary citation | Zhang, L.,Irimia, A.,He, L.,Landais, E.,Rantalainen, K.,Leaman, D.P.,Vollbrecht, T.,Stano, A.,Sands, D.I.,Kim, A.S.,Poignard, P.,Burton, D.R.,Murrell, B.,Ward, A.B.,Zhu, J.,Wilson, I.A.,Zwick, M.B. An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10:5389-5389, 2019 Cited by PubMed: 31772165DOI: 10.1038/s41467-019-12973-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.105 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)