8GJE

HIV-1 Env subtype C CZA97.12 SOSIP.664 in complex with 3BNC117 Fab

Summary for 8GJE

• Entry DOI: 10.2210/pdb8gje/pdb
• EMDB information: 40088
• Descriptor: CZA97.12 SOSIP.664 Envelope glycoprotein gp120, CZA97.12 SOSIP.664 Envelope glycoprotein gp41, 3BNC117 Fab heavy chain, ... (9 entities in total)
• Functional Keywords: hiv envelope, sosip, broadly neutralizing antibody, clade c, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 12
• Total formula weight: 391382.40

Authors

Ozorowski, G.,Lee, J.H.,Ward, A.B. (deposition date: 2023-03-15, release date: 2023-10-18, Last modification date: 2023-11-22)

• Primary citation: Ringe, R.P.,Colin, P.,Ozorowski, G.,Allen, J.D.,Yasmeen, A.,Seabright, G.E.,Lee, J.H.,Antanasijevic, A.,Rantalainen, K.,Ketas, T.,Moore, J.P.,Ward, A.B.,Crispin, M.,Klasse, P.J.; Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.; Plos Pathog., 19:e1011601-e1011601, 2023; PubMed: 37903160; DOI: 10.1371/journal.ppat.1011601

Experimental method

ELECTRON MICROSCOPY (3.4 Å)