5LPN
 
 | | Structure of human Rab10 in complex with the bMERB domain of Mical-1 | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein-methionine sulfoxide oxidase MICAL1, ... | | Authors: | Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Mueller, M.P, Gazdag, E.M. | | Deposit date: | 2016-08-14 | | Release date: | 2016-08-24 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
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6ZSH
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6ZSI
 | | The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members. | | Descriptor: | DI(HYDROXYETHYL)ETHER, EH domain-binding protein 1, MAGNESIUM ION, ... | | Authors: | Rai, A, Bleimling, N, Vetter, I.R, Goody, R.S. | | Deposit date: | 2020-07-15 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.914 Å) | | Cite: | The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members.
Nat Commun, 11, 2020
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6ZSJ
 | | The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members. | | Descriptor: | EH domain-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Rai, A, Bleimling, N, Vetter, I.R, Goody, R.S. | | Deposit date: | 2020-07-15 | | Release date: | 2020-09-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members.
Nat Commun, 11, 2020
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8A4C
 | | Structure of human Rep15:Rab3B complex. | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab15 effector protein, ... | | Authors: | Rai, A, Vetter, I.R, Goody, R.S. | | Deposit date: | 2022-06-10 | | Release date: | 2022-08-10 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.
Nat Commun, 13, 2022
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8A4B
 | | Structure of human Rep15:Rab3B_Q81L complex. | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab15 effector protein, ... | | Authors: | Rai, A, Vetter, I.R, Goody, R.S. | | Deposit date: | 2022-06-10 | | Release date: | 2022-08-10 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.
Nat Commun, 13, 2022
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8A4A
 | | Structure of human Rep15 in complex with bovine Rab3C. | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab15 effector protein, ... | | Authors: | Rai, A, Vetter, I.R, Goody, R.S. | | Deposit date: | 2022-06-10 | | Release date: | 2022-08-10 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.52 Å) | | Cite: | Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.
Nat Commun, 13, 2022
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7O9J
 | | Crystal structure of DyP-type peroxidase from Dictyostelium discoideum in complex with an activated form of oxygen | | Descriptor: | 1,2-ETHANEDIOL, DyPA, OXYGEN MOLECULE, ... | | Authors: | Rai, A, Fedorov, R, Manstein, D.J. | | Deposit date: | 2021-04-16 | | Release date: | 2021-07-14 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural and Biochemical Characterization of a Dye-Decolorizing Peroxidase from Dictyostelium discoideum .
Int J Mol Sci, 22, 2021
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7O9L
 | | Dictyostelium discoideum dye decolorizing peroxidase DyPA in complex with cyanide. | | Descriptor: | 1,2-ETHANEDIOL, CYANIDE ION, DyPA, ... | | Authors: | Rai, A, Fedorov, R, Manstein, D.J. | | Deposit date: | 2021-04-16 | | Release date: | 2021-07-14 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural and Biochemical Characterization of a Dye-Decolorizing Peroxidase from Dictyostelium discoideum .
Int J Mol Sci, 22, 2021
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7ODZ
 | | Dictyostelium discoideum dye decolorizing peroxidase DyPA in complex with an activated form of oxygen and veratryl alcohol | | Descriptor: | 1,2-ETHANEDIOL, DyPA, OXYGEN MOLECULE, ... | | Authors: | Rai, A, Fedorov, R, Manstein, D.J. | | Deposit date: | 2021-04-30 | | Release date: | 2021-07-14 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural and Biochemical Characterization of a Dye-Decolorizing Peroxidase from Dictyostelium discoideum .
Int J Mol Sci, 22, 2021
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5SZI
 | | Structure of human Rab8a in complex with the bMERB domain of Mical-cL | | Descriptor: | MAGNESIUM ION, MICAL C-terminal-like protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Mueller, M.P, Gazdag, E.M. | | Deposit date: | 2016-08-14 | | Release date: | 2016-08-24 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
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5SZH
 | | Structure of human Rab1b in complex with the bMERB domain of Mical-cL | | Descriptor: | MAGNESIUM ION, MICAL C-terminal-like protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Goody, R.S, Mueller, M.P, Gazdag, E.M. | | Deposit date: | 2016-08-14 | | Release date: | 2016-08-24 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
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5SZG
 | | Structure of the bMERB domain of Mical-3 | | Descriptor: | DI(HYDROXYETHYL)ETHER, Protein-methionine sulfoxide oxidase MICAL3 | | Authors: | Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Gazdag, E.M, Mueller, M.P. | | Deposit date: | 2016-08-14 | | Release date: | 2016-08-24 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
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5SZK
 | | Structure of human N-terminally engineered Rab1b in complex with the bMERB domain of Mical-cL | | Descriptor: | MAGNESIUM ION, MICAL C-terminal-like protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Gazdag, E.M, Mueller, M.P. | | Deposit date: | 2016-08-14 | | Release date: | 2016-08-24 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
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5SZJ
 | | Structure of human Rab10 in complex with the bMERB domain of Mical-cL | | Descriptor: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, MICAL C-terminal-like protein, ... | | Authors: | Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Mueller, M.P, Gazdag, E.M. | | Deposit date: | 2016-08-14 | | Release date: | 2016-08-24 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.66 Å) | | Cite: | bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
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2UZ1
 | | 1.65 Angstrom structure of Benzaldehyde Lyase complexed with 2-methyl- 2,4-pentanediol | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, BENZALDEHYDE LYASE, THIAMINE DIPHOSPHATE | | Authors: | Maraite, A, Schmidt, T, Ansorge-Schumacher, M.B, Brzozowski, A.M, Grogan, G. | | Deposit date: | 2007-04-23 | | Release date: | 2007-07-24 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of the Thdp-Dependent Enzyme Benzaldehyde Lyase Refined to 1.65 A Resolution.
Acta Crystallogr.,Sect.F, 63, 2007
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2XRW
 | | Linear binding motifs for JNK and for calcineurin antagonistically control the nuclear shuttling of NFAT4 | | Descriptor: | GLYCEROL, MITOGEN-ACTIVATED PROTEIN KINASE 8, NUCLEAR FACTOR OF ACTIVATED T-CELLS, ... | | Authors: | Barkai, T, Toeoroe, I, Garai, A, Remenyi, A. | | Deposit date: | 2010-09-23 | | Release date: | 2011-09-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | Specificity of Linear Motifs that Bind to a Common Mitogen-Activated Protein Kinase Docking Groove.
Sci. Signal, 5, 2012
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2XS0
 | | Linear binding motifs for JNK and for calcineurin antagonistically control the nuclear shuttling of NFAT4 | | Descriptor: | MITOGEN-ACTIVATED PROTEIN KINASE 8, NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3, ... | | Authors: | Barkai, T, Toeoroe, I, Garai, A, Remenyi, A. | | Deposit date: | 2010-09-24 | | Release date: | 2011-09-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Specificity of Linear Motifs that Bind to a Common Mitogen-Activated Protein Kinase Docking Groove.
Sci. Signal, 5, 2012
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2Y9Q
 | | Crystal structure of human ERK2 complexed with a MAPK docking peptide | | Descriptor: | MAP KINASE-INTERACTING SERINE/THREONINE-PROTEIN KINASE 1, MITOGEN-ACTIVATED PROTEIN KINASE 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Barkai, T, Garai, A, Toeroe, I, Remenyi, A. | | Deposit date: | 2011-02-16 | | Release date: | 2012-02-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Specificity of Linear Motifs that Bind to a Common Mitogen-Activated Protein Kinase Docking Groove.
Sci. Signal, 5, 2012
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2Y8O
 | | Crystal structure of human p38alpha complexed with a MAPK docking peptide | | Descriptor: | DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6, MITOGEN-ACTIVATED PROTEIN KINASE 14 | | Authors: | Barkai, T, Garai, A, Toeroe, I, Remenyi, A. | | Deposit date: | 2011-02-08 | | Release date: | 2012-02-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Specificity of Linear Motifs that Bind to a Common Mitogen-Activated Protein Kinase Docking Groove.
Sci. Signal, 5, 2012
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6TGC
 | | CryoEM structure of the ternary DOCK2-ELMO1-RAC1 complex. | | Descriptor: | Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 | | Authors: | Chang, L, Yang, J, Chang, J.H, Zhang, Z, Boland, A, McLaughlin, S.H, Abu-Thuraia, A, Killoran, R.C, Smith, M.J, Cote, J.F, Barford, D. | | Deposit date: | 2019-11-15 | | Release date: | 2020-07-29 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Nat Commun, 11, 2020
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6TGB
 | | CryoEM structure of the binary DOCK2-ELMO1 complex | | Descriptor: | Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1 | | Authors: | Chang, L, Yang, J, Chang, J.H, Zhang, Z, Boland, A, McLaughlin, S.H, Abu-Thuraia, A, Killoran, R.C, Smith, M.J, Cote, J.F, Barford, D. | | Deposit date: | 2019-11-15 | | Release date: | 2020-07-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Nat Commun, 11, 2020
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8ORS
 | | Knockout of GMC-oxidoreductase genes reveals that functional redundancy preserves mimivirus essential functions | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Putative GMC-type oxidoreductase | | Authors: | Alempic, J.M, Bisio, H, Villalta, A, Santini, S, Lartigue, A, Schmitt, A, Bugnot, C, Notaro, A, Belmudes, L, Adrait, A, Poirot, O, Ptchelkine, D, De Castro, C, Coute, Y, Abergel, C. | | Deposit date: | 2023-04-17 | | Release date: | 2024-04-17 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes.
Microlife, 5, 2024
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8ORH
 | | Knockout of GMC-oxidoreductase genes reveals that functional redundancy preserves mimivirus essential functions | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Putative GMC-type oxidoreductase | | Authors: | Alempic, J.M, Bisio, H, Villalta, A, Santini, S, Lartigue, A, Schmitt, A, Bugnot, C, Notaro, A, Belmudes, L, Adrait, A, Poirot, O, Ptchelkine, D, De Castro, C, Coute, Y, Abergel, C. | | Deposit date: | 2023-04-14 | | Release date: | 2024-04-17 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes.
Microlife, 5, 2024
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6DEV
 | | Human caspase-6 E35K | | Descriptor: | Caspase-6 | | Authors: | Tubeleviciute-Aydin, A, Beautrait, A, Lynham, J, Sharma, G, Gorelik, A, Deny, L.J, Soya, N, Lukacs, G.L, Nagar, B, Marinier, A, LeBlanc, A.C. | | Deposit date: | 2018-05-13 | | Release date: | 2019-03-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.348 Å) | | Cite: | Identification of Allosteric Inhibitors against Active Caspase-6.
Sci Rep, 9, 2019
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