2XRW

Linear binding motifs for JNK and for calcineurin antagonistically control the nuclear shuttling of NFAT4

Summary for 2XRW

Related2XS0
DescriptorMITOGEN-ACTIVATED PROTEIN KINASE 8, NUCLEAR FACTOR OF ACTIVATED T-CELLS\, CYTOPLASMIC 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
Functional Keywordstranscription, mapk signaling pathways, linear binding motif
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm Q12968
Total number of polymer chains2
Total molecular weight45205.72
Authors
Barkai, T.,Toeoroe, I.,Garai, A.,Remenyi, A. (deposition date: 2010-09-23, release date: 2011-09-28, Last modification date: 2012-10-24)
Primary citation
Garai, A.,Zeke, A.,Gogl, G.,Toro, I.,Fordos, F.,Blankenburg, H.,Barkai, T.,Varga, J.,Alexa, A.,Emig, D.,Albrecht, M.,Remenyi, A.
Specificity of Linear Motifs that Bind to a Common Mitogen-Activated Protein Kinase Docking Groove.
Sci. Signal, 5:74-, 2012
PubMed: 23047924 (PDB entries with the same primary citation)
DOI: 10.1126/SCISIGNAL.2003004
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.33 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19250 0.6% 3.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02