2Y9Q

Crystal structure of human ERK2 complexed with a MAPK docking peptide

Summary for 2Y9Q

Entry DOI	10.2210/pdb2y9q/pdb
Related	1PME 1TVO 1WZY
Descriptor	MITOGEN-ACTIVATED PROTEIN KINASE 1, MAP KINASE-INTERACTING SERINE/THREONINE-PROTEIN KINASE 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywords	transferase, signaling, protein-protein interaction
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Nucleus: P28482 Isoform 2: Cytoplasm. Isoform 3: Cytoplasm: Q9BUB5
Total number of polymer chains	2
Total formula weight	44139.50
Authors	Barkai, T.,Garai, A.,Toeroe, I.,Remenyi, A. (deposition date: 2011-02-16, release date: 2012-02-29, Last modification date: 2023-12-20)
Primary citation	Garai, A.,Zeke, A.,Gogl, G.,Toro, I.,Fordos, F.,Blankenburg, H.,Barkai, T.,Varga, J.,Alexa, A.,Emig, D.,Albrecht, M.,Remenyi, A. Specificity of Linear Motifs that Bind to a Common Mitogen-Activated Protein Kinase Docking Groove. Sci. Signal, 5:74-, 2012 Cited by PubMed: 23047924 DOI: 10.1126/SCISIGNAL.2003004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation