8PWZ
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![BU of 8pwz by Molmil](/molmil-images/mine/8pwz) | Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadBD from Mycobacterium tuberculosis | Descriptor: | (3R)-hydroxyacyl-ACP dehydratase subunit HadB, UPF0336 protein Rv0504c | Authors: | Rima, J, Grimoire, Y, Bories, P, Bardou, F, Quemard, A, Bon, C, Mourey, L, Tranier, S. | Deposit date: | 2023-07-22 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.00196719 Å) | Cite: | HadBD dehydratase from Mycobacterium tuberculosis fatty acid synthase type II: A singular structure for a unique function. Protein Sci., 33, 2024
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2NTN
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![BU of 2ntn by Molmil](/molmil-images/mine/2ntn) | Crystal structure of MabA-C60V/G139A/S144L | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] reductase | Authors: | Poncet-Montange, G, Ducasse-Cabanot, S, Quemard, A, Labesse, G, Cohen-Gonsaud, M. | Deposit date: | 2006-11-08 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Lack of dynamics in the MabA active site kills the enzyme activity: practical consequences for drug-design studies ACTA CRYSTALLOGR.,SECT.D, 63, 2007
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1ENZ
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![BU of 1enz by Molmil](/molmil-images/mine/1enz) | CRYSTAL STRUCTURE AND FUNCTION OF THE ISONIAZID TARGET OF MYCOBACTERIUM TUBERCULOSIS | Descriptor: | ENOYL-ACYL CARRIER PROTEIN (ACP) REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Dessen, A, Quemard, A, Blanchard, J.S, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 1995-01-27 | Release date: | 1996-01-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis. Science, 267, 1995
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1ENY
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![BU of 1eny by Molmil](/molmil-images/mine/1eny) | CRYSTAL STRUCTURE AND FUNCTION OF THE ISONIAZID TARGET OF MYCOBACTERIUM TUBERCULOSIS | Descriptor: | ENOYL-ACYL CARRIER PROTEIN (ACP) REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Dessen, A, Quemard, A, Blanchard, J.S, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 1995-01-27 | Release date: | 1996-01-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis. Science, 267, 1995
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1UZM
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![BU of 1uzm by Molmil](/molmil-images/mine/1uzm) | MabA from Mycobacterium tuberculosis | Descriptor: | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE, CESIUM ION | Authors: | Cohen-Gonsaud, M, Ducasse, S, Quemard, A, Labesse, G. | Deposit date: | 2004-03-14 | Release date: | 2005-03-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Crystal Structure of Maba from Mycobacterium Tuberculosis, a Reductase Involved in Long-Chain Fatty Acid Biosynthesis. J.Mol.Biol., 320, 2002
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1UZL
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![BU of 1uzl by Molmil](/molmil-images/mine/1uzl) | MabA from Mycobacterium tuberculosis | Descriptor: | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE, CESIUM ION | Authors: | Cohen-Gonsaud, M, Ducasse, S, Quemard, A, Labesse, G. | Deposit date: | 2004-03-14 | Release date: | 2005-03-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Maba from Mycobacterium Tuberculosis, a Reductase Involved in Long-Chain Fatty Acid Biosynthesis. J.Mol.Biol., 320, 2002
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1UZN
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![BU of 1uzn by Molmil](/molmil-images/mine/1uzn) | MabA from Mycobacterium tuberculosis | Descriptor: | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE, CESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Cohen-Gonsaud, M, Ducasse, S, Quemard, A, Labesse, G. | Deposit date: | 2004-03-14 | Release date: | 2005-03-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Crystal Structure of Maba from Mycobacterium Tuberculosis, a Reductase Involved in Long-Chain Fatty Acid Biosynthesis. J.Mol.Biol., 320, 2002
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5L84
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![BU of 5l84 by Molmil](/molmil-images/mine/5l84) | |
5I0K
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![BU of 5i0k by Molmil](/molmil-images/mine/5i0k) | |
5NJI
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![BU of 5nji by Molmil](/molmil-images/mine/5nji) | Structure of the dehydratase domain of PpsC from Mycobacterium tuberculosis in complex with C12:1-CoA | Descriptor: | Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsC, ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (~{E})-dodec-2-enethioate | Authors: | Gavalda, S, Faille, A, Mourey, L, Pedelacq, J.D. | Deposit date: | 2017-03-28 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases. J. Mol. Biol., 429, 2017
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4OOC
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![BU of 4ooc by Molmil](/molmil-images/mine/4ooc) | |
4OKI
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![BU of 4oki by Molmil](/molmil-images/mine/4oki) | |
2FK8
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![BU of 2fk8 by Molmil](/molmil-images/mine/2fk8) | |
2FK7
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![BU of 2fk7 by Molmil](/molmil-images/mine/2fk7) | |
1ZID
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![BU of 1zid by Molmil](/molmil-images/mine/1zid) | |
3HA5
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![BU of 3ha5 by Molmil](/molmil-images/mine/3ha5) | |
3HA3
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![BU of 3ha3 by Molmil](/molmil-images/mine/3ha3) | |
3HA7
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![BU of 3ha7 by Molmil](/molmil-images/mine/3ha7) | |
3TZW
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![BU of 3tzw by Molmil](/molmil-images/mine/3tzw) | Crystal structure of a fragment containing the acyltransferase domain of Pks13 from Mycobacterium tuberculosis in the orthorhombic apoform at 2.6 A | Descriptor: | 1,2-ETHANEDIOL, 12-mer peptide, Polyketide synthase PKS13, ... | Authors: | Bergeret, F, Pedelacq, J.D, Mourey, L, Bon, C. | Deposit date: | 2011-09-28 | Release date: | 2012-08-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13 J.Biol.Chem., 287, 2012
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3TZY
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![BU of 3tzy by Molmil](/molmil-images/mine/3tzy) | Crystal structure of a fragment containing the acyltransferase domain of Pks13 from Mycobacterium tuberculosis in the palmitoylated form at 2.2 A | Descriptor: | 12-mer peptide, GLYCEROL, PALMITIC ACID, ... | Authors: | Bergeret, F, Pedelacq, J.D, Mourey, L, Bon, C. | Deposit date: | 2011-09-28 | Release date: | 2012-08-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13 J.Biol.Chem., 287, 2012
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3TZX
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![BU of 3tzx by Molmil](/molmil-images/mine/3tzx) | Crystal structure of a fragment containing the acyltransferase domain of Pks13 from Mycobacterium tuberculosis in tetragonal apo form at 2.3 A | Descriptor: | 12-mer peptide, GLYCEROL, Polyketide synthase PKS13, ... | Authors: | Bergeret, F, Pedelacq, J.D, Mourey, L, Bon, C. | Deposit date: | 2011-09-28 | Release date: | 2012-08-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13 J.Biol.Chem., 287, 2012
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3TZZ
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![BU of 3tzz by Molmil](/molmil-images/mine/3tzz) | Crystal structure of a fragment containing the acyltransferase domain of Pks13 from Mycobacterium tuberculosis in the carboxypalmitoylated form at 2.5 A | Descriptor: | 12-mer peptide, 2-(2-METHOXYETHOXY)ETHANOL, GLYCEROL, ... | Authors: | Bergeret, F, Pedelacq, J.D, Mourey, L, Bon, C. | Deposit date: | 2011-09-28 | Release date: | 2012-08-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase pks13 J.Biol.Chem., 287, 2012
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