8PWZ

Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadBD from Mycobacterium tuberculosis

Summary for 8PWZ

• Entry DOI: 10.2210/pdb8pwz/pdb
• Descriptor: UPF0336 protein Rv0504c, (3R)-hydroxyacyl-ACP dehydratase subunit HadB (3 entities in total)
• Functional Keywords: (3r)-hydroxyacyl-acp dehydratase, fas-ii system, mycolic acid synthesis, lyase
• Biological source: Mycobacterium tuberculosis H37Rv; More
• Total number of polymer chains: 2
• Total formula weight: 35507.23

Authors

Rima, J.,Grimoire, Y.,Bories, P.,Bardou, F.,Quemard, A.,Bon, C.,Mourey, L.,Tranier, S. (deposition date: 2023-07-22, release date: 2024-03-27)

• Primary citation: Bories, P.,Rima, J.,Tranier, S.,Marcoux, J.,Grimoire, Y.,Tomaszczyk, M.,Launay, A.,Fata, K.,Marrakchi, H.,Burlet-Schiltz, O.,Mourey, L.,Ducoux-Petit, M.,Bardou, F.,Bon, C.,Quemard, A.; HadBD dehydratase from Mycobacterium tuberculosis fatty acid synthase type II: A singular structure for a unique function.; Protein Sci., 33:e4964-e4964, 2024; PubMed: 38501584; DOI: 10.1002/pro.4964

Experimental method

X-RAY DIFFRACTION (2.00196723217 Å)