1ZID

LONG FATTY ACID CHAIN ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH AN ISONICOTINIC-ACYL-NADH INHIBITOR

Summary for 1ZID

Entry DOI	10.2210/pdb1zid/pdb
Descriptor	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywords	oxidoreductase, inha enzyme, isoniazid, modified nadh, enoyl-acp reductase, tuberculosis, mycolic acid biosynthesis, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	29162.08
Authors	Rozwarski, D.A.,Jacobs Jr., W.R.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 1997-03-25, release date: 1998-03-25, Last modification date: 2023-08-09)
Primary citation	Rozwarski, D.A.,Grant, G.A.,Barton, D.H.,Jacobs Jr., W.R.,Sacchettini, J.C. Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis. Science, 279:98-102, 1998 Cited by PubMed: 9417034 DOI: 10.1126/science.279.5347.98 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation