1ZID
LONG FATTY ACID CHAIN ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH AN ISONICOTINIC-ACYL-NADH INHIBITOR
Summary for 1ZID
Entry DOI | 10.2210/pdb1zid/pdb |
Descriptor | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE (3 entities in total) |
Functional Keywords | oxidoreductase, inha enzyme, isoniazid, modified nadh, enoyl-acp reductase, tuberculosis, mycolic acid biosynthesis, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 29162.08 |
Authors | Rozwarski, D.A.,Jacobs Jr., W.R.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 1997-03-25, release date: 1998-03-25, Last modification date: 2024-05-22) |
Primary citation | Rozwarski, D.A.,Grant, G.A.,Barton, D.H.,Jacobs Jr., W.R.,Sacchettini, J.C. Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis. Science, 279:98-102, 1998 Cited by PubMed: 9417034DOI: 10.1126/science.279.5347.98 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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