3HA3

Crystal structure of HMA (MMAA4) from mycobacterium tuberculosis complexed with S-adenosylhomocysteine

Summary for 3HA3

• Entry DOI: 10.2210/pdb3ha3/pdb
• Related: 2FK7 2FK8 3HA5 3HA7
• Descriptor: METHOXY MYCOLIC ACID SYNTHASE 4, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
• Functional Keywords: s-adenosylmethionine-dependent methyltransferase fold, methyltransferase, transferase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 36905.72

Authors

Boissier, F.,Vaubourgeix, J.,Julien, S.,Mourey, L. (deposition date: 2009-05-01, release date: 2009-05-12, Last modification date: 2023-09-06)

• Primary citation: Vaubourgeix, J.,Bardou, F.,Boissier, F.,Julien, S.,Constant, P.,Ploux, O.,Daffe, M.,Quemard, A.,Mourey, L.; SADAE, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)