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6BF6
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BU of 6bf6 by Molmil
Cryo-EM structure of human insulin degrading enzyme
分子名称: Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BFC
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BU of 6bfc by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称: Insulin, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2017-12-27
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Y
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BU of 6b7y by Molmil
Cryo-EM structure of human insulin degrading enzyme
分子名称: Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-05
公開日2017-11-08
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B3Q
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BU of 6b3q by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称: Insulin, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-09-22
公開日2017-11-22
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Z
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BU of 6b7z by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain
分子名称: FAB H11 heavy chain, FAB H11 light chain, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-05
公開日2018-01-10
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF9
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BU of 6bf9 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
分子名称: Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-02-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF7
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BU of 6bf7 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
分子名称: Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-02-07
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6UPL
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BU of 6upl by Molmil
Structure of FACT_subnucleosome complex 2
分子名称: DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ...
著者Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K.
登録日2019-10-17
公開日2019-12-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献FACT caught in the act of manipulating the nucleosome.
Nature, 577, 2020
6UPK
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BU of 6upk by Molmil
Structure of FACT_subnucleosome complex 1
分子名称: DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ...
著者Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K.
登録日2019-10-17
公開日2019-12-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献FACT caught in the act of manipulating the nucleosome.
Nature, 577, 2020
5TKJ
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BU of 5tkj by Molmil
Structure of vaccine-elicited diverse HIV-1 neutralizing antibody vFP1.01 in complex with HIV-1 fusion peptide residue 512-519
分子名称: HIV-1 fusion peptide residue 512-519, SULFATE ION, vFP1.01 chimeric mouse antibody heavy chain, ...
著者Xu, K, Liu, K, Kwong, P.D.
登録日2016-10-06
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.118 Å)
主引用文献Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
5TKK
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BU of 5tkk by Molmil
Structure of mouse vaccination-elicited HIV neutralizing antibody vFP5.01 in complex with HIV-1 fusion peptide residue 512-519
分子名称: HIV-1 fusion peptide residue 512-519, mouse antibody vFP5.01 heavy chain, mouse antibody vFP5.01 light chain
著者Xu, K, Liu, K, Kwong, P.D.
登録日2016-10-06
公開日2018-04-04
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
5WOB
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BU of 5wob by Molmil
Crystal Structure Analysis of Fab1-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin
分子名称: IDE-bound Fab heavy chain, IDE-bound Fab light chain, Insulin, ...
著者McCord, L.A, Liang, W.G, Farcasanu, M, Wang, A.G, Koide, S, Tang, W.J.
登録日2017-08-01
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6XOS
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BU of 6xos by Molmil
CryoEM structure of human presequence protease in partial open state 1
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOU
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BU of 6xou by Molmil
CryoEM structure of human presequence protease in open state
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOV
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BU of 6xov by Molmil
CryoEM structure of human presequence protease in partial closed state 1
分子名称: Amyloid-beta precursor protein, Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOT
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BU of 6xot by Molmil
CryoEM structure of human presequence protease in partial open state 2
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6OT1
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BU of 6ot1 by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
分子名称: 0PV-b.01 heavy, 0PV-b.01 light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorman, J, Kwong, P.D.
登録日2019-05-02
公開日2019-08-07
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6OSY
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BU of 6osy by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
分子名称: 0PV-a.01 Heavy, 0PV-a.01 Light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorman, J, Kwong, P.D.
登録日2019-05-02
公開日2019-07-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
7RZI
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BU of 7rzi by Molmil
Insulin Degrading Enzyme pC/pC
分子名称: Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain
著者Mancl, J.M, Liang, W.G, Tang, W.J.
登録日2021-08-27
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
7RZE
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BU of 7rze by Molmil
Insulin Degrading Enzyme pO/pC
分子名称: Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain
著者Mancl, J.M, Liang, W.G, Tang, W.J.
登録日2021-08-27
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
7RZH
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BU of 7rzh by Molmil
Insulin Degrading Enzyme O/O
分子名称: Cysteine-free Insulin-degrading enzyme
著者Mancl, J.M, Liang, W.G, Tang, W.J.
登録日2021-08-27
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
7RZG
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BU of 7rzg by Molmil
Insulin Degrading Enzyme O/pO
分子名称: Cysteine-free Insulin-degrading enzyme
著者Mancl, J.M, Liang, W.G, Tang, W.J.
登録日2021-08-27
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
7RZF
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BU of 7rzf by Molmil
Insulin Degrading Enzyme O/pC
分子名称: Cysteine-free Insulin-degrading enzyme, Insulin A chain, Insulin B chain
著者Mancl, J.M, Liang, W.G, Tang, W.J.
登録日2021-08-27
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Ensemble cryoEM reveals a substrate-induced shift in the conformational dynamics of human insulin degrading enzyme
To be published
6VFT
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BU of 6vft by Molmil
Crystal structure of human delta protocadherin 17 EC1-EC4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Harrison, O.J, Brasch, J, Shapiro, L.
登録日2020-01-06
公開日2020-03-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.71 Å)
主引用文献Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VG4
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BU of 6vg4 by Molmil
Human protocadherin 10 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Harrison, O.J, Brasch, J, Shapiro, L.
登録日2020-01-07
公開日2020-03-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.298 Å)
主引用文献Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020

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件を2024-05-15に公開中

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