5OGI
| Complex of a binding protein and human adenovirus C 5 hexon | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Schmid, M, Ernst, P, Honegger, A, Suomalainen, M, Zimmermann, M, Braun, L, Stauffer, S, Thom, C, Dreier, B, Eibauer, M, Kipar, A, Vogel, V, Greber, U.F, Medalia, O, Plueckthun, A. | 登録日 | 2017-07-13 | 公開日 | 2018-02-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control. Nat Commun, 9, 2018
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8P9E
| Crystal structure of wild type p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11 | 分子名称: | Darpin 1810 F11, GLYCEROL, Isoform 2 of Tumor protein 63, ... | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2023-06-05 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
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5AAO
| Crystal structure of fluorogen-activating designed ankyrin repeat protein (DARPin) dimer in complex with malachite green | 分子名称: | 4-[[4-(dimethylamino)cyclohexa-2,5-dien-1-ylidene]-(4-methoxyphenyl)methyl]-N,N-dimethyl-aniline, FAD3210 | 著者 | Batyuk, A, Schuetz, M, Kummer, L, Wu, Y, Mittl, P, Plueckthun, A. | 登録日 | 2015-07-27 | 公開日 | 2016-02-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools. J. Mol. Biol., 428, 2016
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7TXD
| Cryo-EM structure of BG505 SOSIP HIV-1 Env trimer in complex with CD4 receptor (D1D2) and broadly neutralizing darpin bnD.9 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing darpin bnd.9, ... | 著者 | Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L. | 登録日 | 2022-02-08 | 公開日 | 2023-04-12 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | 主引用文献 | Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization. Nat.Struct.Mol.Biol., 30, 2023
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8P9D
| Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 A2 | 分子名称: | Darpin 1810 A2, Tumor protein 63, Tumor protein p73 | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2023-06-05 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
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8P9C
| Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11 | 分子名称: | 1,2-ETHANEDIOL, Darpin 1810 F11, Tumor protein 63, ... | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2023-06-05 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
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7QNP
| Designed Armadillo repeat protein N(A4)M4C(AII) co-crystallized with hen egg white lysozyme | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, Designed Armadillo Repeat Protein N(A4)M4C(AII), ... | 著者 | Michel, E, Mittl, P.R.E, Plueckthun, A. | 登録日 | 2021-12-21 | 公開日 | 2022-06-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.586 Å) | 主引用文献 | Improved Repeat Protein Stability by Combined Consensus and Computational Protein Design. Biochemistry, 62, 2023
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7DNG
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7DNF
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7DNE
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7Z7E
| Crystal structure of p63 DNA binding domain in complex with inhibitory DARPin G4 | 分子名称: | DARPIN, Isoform 4 of Tumor protein 63, ZINC ION | 著者 | Strubel, A, Gebel, J, Chaikuad, A, Muenick, P, Doetsch, V. | 登録日 | 2022-03-15 | 公開日 | 2022-06-29 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell Death Differ., 29, 2022
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7Z73
| Crystal structure of p63 tetramerization domain in complex with darpin 8F1 | 分子名称: | Darpin 8F1, Isoform 2 of Tumor protein 63 | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-03-14 | 公開日 | 2022-07-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell Death Differ., 29, 2022
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7Z72
| Crystal structure of p63 SAM in complex with darpin A5 | 分子名称: | DI(HYDROXYETHYL)ETHER, Darpin A5, Isoform 9 of Tumor protein 63 | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-03-14 | 公開日 | 2022-07-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell Death Differ., 29, 2022
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7Z71
| Crystal structure of p63 DBD in complex with darpin C14 | 分子名称: | Darpin C14, Isoform 4 of Tumor protein 63, ZINC ION | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-03-14 | 公開日 | 2022-07-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell Death Differ., 29, 2022
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5AEI
| Designed Armadillo repeat protein YIIIM5AII in complex with peptide (KR)5 | 分子名称: | ACETATE ION, CALCIUM ION, DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII, ... | 著者 | Hansen, S, Tremmel, D, Madhurantakam, C, Reichen, C, Mittl, P, Plueckthun, A. | 登録日 | 2015-08-31 | 公開日 | 2016-03-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structure and Energetic Contributions of a Designed Modular Peptide-Binding Protein with Picomolar Affinity. J.Am.Chem.Soc., 138, 2016
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1TOL
| FUSION OF N-TERMINAL DOMAIN OF THE MINOR COAT PROTEIN FROM GENE III IN PHAGE M13, AND C-TERMINAL DOMAIN OF E. COLI PROTEIN-TOLA | 分子名称: | PROTEIN (FUSION PROTEIN CONSISTING OF MINOR COAT PROTEIN, GLYCINE RICH LINKER, TOLA, ... | 著者 | Lubkowski, J, Wlodawer, A, Hennecke, F, Plueckthun, A. | 登録日 | 1999-05-17 | 公開日 | 1999-05-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Filamentous phage infection: crystal structure of g3p in complex with its coreceptor, the C-terminal domain of TolA. Structure Fold.Des., 7, 1999
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2IMM
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2P2C
| Inhibition of caspase-2 by a designed ankyrin repeat protein (DARPin) | 分子名称: | Caspase-2 | 著者 | Roschitzki Voser, H, Briand, C, Capitani, G, Gruetter, M.G. | 登録日 | 2007-03-07 | 公開日 | 2007-05-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism. Structure, 15, 2007
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7Z7C
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2RU5
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2RU4
| Designed Armadillo Repeat Protein Self-ASsembled Complex (YIIM2-MAII) | 分子名称: | Armadillo Repeat Protein, C-terminal fragment, MAII, ... | 著者 | Zerbe, O, Christen, M.T, Plueckthun, A, Watson, R.P. | 登録日 | 2013-11-22 | 公開日 | 2014-07-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Spontaneous self-assembly of engineered armadillo repeat protein fragments into a folded structure Structure, 22, 2014
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4ATZ
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4PLS
| Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure. | 分子名称: | ACETATE ION, Arm00010, CALCIUM ION | 著者 | Reichen, C, Madhurantakam, C, Plueckthun, A, Mittl, P.R. | 登録日 | 2014-05-19 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure. Protein Sci., 23, 2014
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4PLR
| Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure. | 分子名称: | Arm00008, CALCIUM ION | 著者 | Reichen, C, Madhurantakam, C, Plueckthun, A, Mittl, P. | 登録日 | 2014-05-19 | 公開日 | 2014-08-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of designed armadillo repeat proteins: Implications of construct design and crystallization conditions on overall structure. Protein Sci., 23, 2014
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4K5A
| Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W | 分子名称: | Bcl-2-like protein 2, Designed Ankyrin Repeat Protein 013_D12 | 著者 | Schilling, J, Schoeppe, J, Sauer, E, Plueckthun, A. | 登録日 | 2013-04-14 | 公開日 | 2014-04-16 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Co-Crystallization with Conformation-Specific Designed Ankyrin Repeat Proteins Explains the Conformational Flexibility of BCL-W J.Mol.Biol., 426, 2014
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