7DNG

DARPin 63_B7 in complex with linear V3-crown (MN) peptide

Summary for 7DNG

Entry DOI	10.2210/pdb7dng/pdb
Descriptor	DARPin 63_B7, linear V3-crown (MN) peptide (3 entities in total)
Functional Keywords	designed ankyrin repeat proteins, protein design, protein engineering, anti-hiv, de novo protein
Biological source	synthetic construct More
Total number of polymer chains	2
Total formula weight	20005.42
Authors	Wu, Y.,Plueckthun, A. (deposition date: 2020-12-09, release date: 2021-12-15, Last modification date: 2023-11-29)
Primary citation	Friedrich, N.,Stiegeler, E.,Glogl, M.,Lemmin, T.,Hansen, S.,Kadelka, C.,Wu, Y.,Ernst, P.,Maliqi, L.,Foulkes, C.,Morin, M.,Eroglu, M.,Liechti, T.,Ivan, B.,Reinberg, T.,Schaefer, J.V.,Karakus, U.,Ursprung, S.,Mann, A.,Rusert, P.,Kouyos, R.D.,Robinson, J.A.,Gunthard, H.F.,Pluckthun, A.,Trkola, A. Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization. Nat Commun, 12:6705-6705, 2021 Cited by PubMed: 34795280 DOI: 10.1038/s41467-021-27075-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.42 Å)

Structure validation