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2P2C

Inhibition of caspase-2 by a designed ankyrin repeat protein (DARPin)

Summary for 2P2C
Entry DOI10.2210/pdb2p2c/pdb
Related1MJO 1PYO
DescriptorCaspase-2, ... (4 entities in total)
Functional Keywordsapoptosis, caspase, caspase-2, inhibition, protein design, protein libraries, designed ankyrin repeat proteins, ribosome display, hydrolase
Biological sourceHomo sapiens (human)
More
Total number of polymer chains18
Total formula weight297019.76
Authors
Roschitzki Voser, H.,Briand, C.,Capitani, G.,Gruetter, M.G. (deposition date: 2007-03-07, release date: 2007-05-22, Last modification date: 2023-08-30)
Primary citationSchweizer, A.,Roschitzki-Voser, H.,Amstutz, P.,Briand, C.,Gulotti-Georgieva, M.,Prenosil, E.,Binz, H.K.,Capitani, G.,Baici, A.,Pluckthun, A.,Grutter, M.G.
Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism.
Structure, 15:625-636, 2007
Cited by
PubMed: 17502107
DOI: 10.1016/j.str.2007.03.014
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.24 Å)
Structure validation

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