8DGU
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8DGV
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8DGW
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8AN8
| Crystal structure of wild-type c-MET bound by compound 7. | 分子名称: | 3-[bis(fluoranyl)methyl]-~{N}-methyl-~{N}-[(1~{R})-8-methyl-5-(3-methyl-1~{H}-indazol-6-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]pyridine-2-carboxamide, Hepatocyte growth factor receptor, SULFATE ION | 著者 | Collie, G.W. | 登録日 | 2022-08-04 | 公開日 | 2022-08-31 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.394 Å) | 主引用文献 | Discovery of a selective c-MET inhibitor with a novel binding mode. Bioorg.Med.Chem.Lett., 75, 2022
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8ANS
| Crystal structure of D1228V c-MET bound by compound 1. | 分子名称: | 3-[bis(fluoranyl)methyl]-~{N}-methyl-~{N}-[(1~{R})-8-methyl-5-(3-methyl-1~{H}-indazol-6-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]pyridine-2-carboxamide, GLYCEROL, Hepatocyte growth factor receptor | 著者 | Collie, G.W. | 登録日 | 2022-08-05 | 公開日 | 2022-08-31 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Discovery of a selective c-MET inhibitor with a novel binding mode. Bioorg.Med.Chem.Lett., 75, 2022
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5ULA
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7LQ7
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV503 and COVA1-16 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 heavy chain, COVA1-16 light chain, ... | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | 登録日 | 2021-02-13 | 公開日 | 2021-09-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern. Sci Transl Med, 13, 2021
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4YPG
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5YVF
| Crystal structure of BFA1 | 分子名称: | BFA1 | 著者 | Pu, H, Zhang, L, Duan, Z.K, Peng, L.W, Liu, L. | 登録日 | 2017-11-25 | 公開日 | 2018-08-08 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | 主引用文献 | Nucleus-Encoded Protein BFA1 Promotes Efficient Assembly of the Chloroplast ATP Synthase Coupling Factor 1. Plant Cell, 30, 2018
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7T62
| GPC2 HEP CT3 complex | 分子名称: | CT3, Glypican-2 | 著者 | Zhu, J, Cachau, R, De Val Alda, N, Li, N, Ho, M. | 登録日 | 2021-12-13 | 公開日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (21 Å) | 主引用文献 | CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice. Cell Rep Med, 2, 2021
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7TP3
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K288.2 | 分子名称: | CACODYLATE ION, K288.2 heavy chain, K288.2 light chain, ... | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | 登録日 | 2022-01-24 | 公開日 | 2022-02-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. Sci Transl Med, 14, 2022
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7TP4
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K398.22 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, K398.22 heavy chain, ... | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | 登録日 | 2022-01-24 | 公開日 | 2022-02-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. Sci Transl Med, 14, 2022
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6H1E
| Crystal structure of C21orf127-TRMT112 in complex with SAH and H4 peptide | 分子名称: | HemK methyltransferase family member 2, Histone H4 peptide, Multifunctional methyltransferase subunit TRM112-like protein, ... | 著者 | Wang, S, Hermann, B, Metzger, E, Peng, L, Einsle, O, Schuele, R. | 登録日 | 2018-07-11 | 公開日 | 2019-05-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells. Nat.Struct.Mol.Biol., 26, 2019
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6H1D
| Crystal structure of C21orf127-TRMT112 in complex with SAH | 分子名称: | HemK methyltransferase family member 2, Multifunctional methyltransferase subunit TRM112-like protein, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Wang, S, Hermann, B, Metzger, E, Peng, L, Einsle, O, Schuele, R. | 登録日 | 2018-07-11 | 公開日 | 2019-05-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells. Nat.Struct.Mol.Biol., 26, 2019
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8SDF
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8SIT
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8SDG
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8SIS
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8SIR
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8SIQ
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8SDH
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8SPE
| Crystal structure of Bax core domain BH3-groove dimer - tetrameric fraction P31 | 分子名称: | 1,2-ETHANEDIOL, Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, ... | 著者 | Miller, M.S, Cowan, A.D, Colman, P.M, Czabotar, P.E. | 登録日 | 2023-05-03 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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8SPZ
| Crystal structure of Bax core domain BH3-groove dimer - hexameric fraction with dioctanoyl phosphatidylserine | 分子名称: | Apoptosis regulator BAX, SULFATE ION | 著者 | Cowan, A.D, Colman, P.M, Czabotar, P.E, Miller, M.S. | 登録日 | 2023-05-04 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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8SPF
| Crystal structure of Bax core domain BH3-groove dimer - hexameric fraction with 2-stearoyl lysoPC | 分子名称: | 1,2-ETHANEDIOL, Apoptosis regulator BAX, DODECANE, ... | 著者 | Cowan, A.D, Miller, M.S, Czabotar, P.E, Colman, P.M. | 登録日 | 2023-05-03 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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8SVK
| Crystal structure of Bax D71N core domain BH3-groove dimer | 分子名称: | Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | 著者 | Miller, M.S, Czabotar, P.E, Colman, P.M. | 登録日 | 2023-05-16 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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