3F73
| Alignment of guide-target seed duplex within an argonaute silencing complex | Descriptor: | ARGONAUTE, DNA (5'-D(P*DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DAP*DGP*DGP*DTP*DTP*DGP*DTP*DA*DTP*DAP*DGP*DT)-3'), MAGNESIUM ION, ... | Authors: | Wang, Y, Li, H, Sheng, G, Juranek, S, Tuschl, T, Patel, D.J. | Deposit date: | 2008-11-07 | Release date: | 2008-12-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. Nature, 456, 2008
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3QZS
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3RB3
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3RBD
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3QZV
| Crystal Structure of BPTF PHD-linker-bromo in complex with histone H4K12ac peptide | Descriptor: | Histone H4, Nucleosome-remodeling factor subunit BPTF, ZINC ION | Authors: | Li, H, Ruthenburg, A.J, Patel, D.J. | Deposit date: | 2011-03-07 | Release date: | 2011-06-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions. Cell(Cambridge,Mass.), 145, 2011
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3RIC
| Crystal Structure of D48V||A47D mutant of Human Glycolipid Transfer Protein complexed with 3-O-sulfo-galactosylceramide containing nervonoyl acyl chain (24:1) | Descriptor: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, Glycolipid transfer protein | Authors: | Samygina, V, Ochoa-Lizarralde, B, Patel, D.J, Brown, R.E, Malinina, L. | Deposit date: | 2011-04-13 | Release date: | 2012-02-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein. Structure, 19, 2011
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3RIU
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3RB4
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5U34
| Crystal structure of AacC2c1-sgRNA binary complex | Descriptor: | CRISPR-associated endonuclease C2c1, sgRNA | Authors: | Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J. | Deposit date: | 2016-12-01 | Release date: | 2017-01-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.255 Å) | Cite: | PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease. Cell, 167, 2016
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5U30
| Crystal structure of AacC2c1-sgRNA-extended target DNA ternary complex | Descriptor: | CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ... | Authors: | Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J. | Deposit date: | 2016-12-01 | Release date: | 2017-01-25 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease. Cell, 167, 2016
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5U31
| Crystal structure of AacC2c1-sgRNA-8mer substrate DNA ternary complex | Descriptor: | CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ... | Authors: | Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J. | Deposit date: | 2016-12-01 | Release date: | 2017-01-25 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease. Cell, 167, 2016
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5U33
| Crystal structure of AacC2c1-sgRNA-extended non-target DNA ternary complex | Descriptor: | CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ... | Authors: | Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J. | Deposit date: | 2016-12-01 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.75 Å) | Cite: | PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease. Cell, 167, 2016
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5VW1
| Crystal structure of SpyCas9-sgRNA-AcrIIA4 ternary complex | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9/Csn1, DI(HYDROXYETHYL)ETHER, ... | Authors: | Yang, H, Patel, D.J. | Deposit date: | 2017-05-21 | Release date: | 2017-06-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.598 Å) | Cite: | Inhibition Mechanism of an Anti-CRISPR Suppressor AcrIIA4 Targeting SpyCas9. Mol. Cell, 67, 2017
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2F6N
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2F8S
| Crystal structure of Aa-Ago with externally-bound siRNA | Descriptor: | 5'-R(P*AP*GP*AP*CP*AP*GP*CP*AP*UP*AP*UP*AP*UP*GP*CP*UP*GP*UP*CP*UP*UP*U)-3', Argonaute protein | Authors: | Yuan, Y.R, Chen, H.Y, Patel, D.J. | Deposit date: | 2005-12-03 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Potential Protein-RNA Recognition Event along the RISC-Loading Pathway from the Structure of A. aeolicus Argonaute with Externally Bound siRNA. Structure, 14, 2006
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2EVS
| Crystal structure of human Glycolipid Transfer Protein complexed with n-hexyl-beta-D-glucoside | Descriptor: | DECANE, Glycolipid transfer protein, HEXANE, ... | Authors: | Malinina, L, Malakhova, M.L, Kanack, A.T, Abagyan, R, Brown, R.E, Patel, D.J. | Deposit date: | 2005-10-31 | Release date: | 2006-11-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure. Plos Biol., 4, 2006
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2EVT
| Crystal structure of D48V mutant of human Glycolipid Transfer Protein | Descriptor: | Glycolipid transfer protein, HEXANE | Authors: | Malinina, L, Malakhova, M.L, Teplov, A, Brown, R.E, Patel, D.J. | Deposit date: | 2005-10-31 | Release date: | 2005-11-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure. Plos Biol., 4, 2006
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2EUK
| Crystal Structure of Human Glycolipid Transfer Protein complexed with 24:1 Galactosylceramide | Descriptor: | (15E)-TETRACOS-15-ENOIC ACID, Glycolipid transfer protein, N-OCTANE, ... | Authors: | Malinina, L, Malakhova, M.L, Kanack, A.T, Abagyan, R, Brown, R.E, Patel, D.J. | Deposit date: | 2005-10-28 | Release date: | 2006-11-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure. Plos Biol., 4, 2006
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2F8T
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2F6J
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2FSA
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2FUI
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2FUU
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2GKU
| Monomeric human telomere DNA tetraplex with 3+1 strand fold topology, two edgewise loops and double-chain reversal loop, NMR, 12 structures | Descriptor: | Human telomere DNA | Authors: | Luu, K.N, Phan, A.T, Kuryavyi, V.V, Lacroix, L, Patel, D.J. | Deposit date: | 2006-04-03 | Release date: | 2006-08-15 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structure of the human telomere in k(+) solution: an intramolecular (3 + 1) g-quadruplex scaffold. J.Am.Chem.Soc., 128, 2006
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2H68
| Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex | Descriptor: | WD-repeat protein 5 | Authors: | Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L. | Deposit date: | 2006-05-30 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat.Struct.Mol.Biol., 13, 2006
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