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2L8C
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NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)2 Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1 - UU pair with zero hydrogen bond pairs
Descriptor: RNA (5'-R(*CP*CP*GP*CP*UP*GP*CP*GP*G)-3')
Authors:Parkesh, R, Fountain, M.A, Disney, M.D.
Deposit date:2011-01-07
Release date:2011-02-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)(2) Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1.
Biochemistry, 50, 2011
2L8W
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BU of 2l8w by Molmil
r(CCGCUGCGG)2 UU Internal Loop Found in Myotonic Dystrophy Type 1 - UU pair with two hydrogen bond pairs
Descriptor: RNA (5'-R(*CP*CP*GP*CP*UP*GP*CP*GP*G)-3')
Authors:Parkesh, R, Fountain, M, Disney, M.
Deposit date:2011-01-26
Release date:2011-02-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)(2) Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1.
Biochemistry, 50, 2011
2L8U
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BU of 2l8u by Molmil
NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)2 Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1 - UU pair with one hydrogen bond pair
Descriptor: RNA (5'-R(*CP*CP*GP*CP*UP*GP*CP*GP*G)-3')
Authors:Parkesh, R, Fountain, M.A, Disney, M.D.
Deposit date:2011-01-25
Release date:2011-02-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)(2) Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1.
Biochemistry, 50, 2011
5DD1
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BU of 5dd1 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
Descriptor: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN
Authors:Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:2015-08-24
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.597 Å)
Cite:Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
3SZX
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BU of 3szx by Molmil
Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Descriptor: RNA (5'-R(P*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3')
Authors:Kumar, A, Park, H, Pengfei, F, Parkesh, R, Guo, M, Nettles, K.W, Disney, M.D.
Deposit date:2011-07-19
Release date:2012-04-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
3SYW
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BU of 3syw by Molmil
Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Descriptor: PHOSPHATE ION, RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3')
Authors:Kumar, A, Park, H, Pengfei, F, Parkesh, R, Guo, M, Nettles, K.W, Disney, M.D.
Deposit date:2011-07-18
Release date:2012-04-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
5DD0
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BU of 5dd0 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
Descriptor: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB HEAVY LIGHT, oligo peptide
Authors:Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:2015-08-24
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.488 Å)
Cite:Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
4QF1
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BU of 4qf1 by Molmil
Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ...
Authors:Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:2014-05-19
Release date:2015-02-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved.
Immunity, 41, 2014
1Q67
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BU of 1q67 by Molmil
Crystal structure of Dcp1p
Descriptor: Decapping protein involved in mRNA degradation-Dcp1p
Authors:She, M, Decker, C.J, Liu, Y, Chen, N, Parker, R, Song, H.
Deposit date:2003-08-12
Release date:2004-03-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Dcp1p and its functional implications in mRNA decapping
Nat.Struct.Mol.Biol., 11, 2004
2GK6
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BU of 2gk6 by Molmil
Structural and Functional insights into the human Upf1 helicase core
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Cheng, Z, Muhlrad, D, Parker, R, Song, H.
Deposit date:2006-03-31
Release date:2007-01-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional insights into the human Upf1 helicase core
Embo J., 26, 2007
2GJK
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BU of 2gjk by Molmil
Structural and functional insights into the human Upf1 helicase core
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Regulator of nonsense transcripts 1
Authors:Cheng, Z, Muhlrad, D, Parker, R, Song, H.
Deposit date:2006-03-31
Release date:2007-01-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and functional insights into the human Upf1 helicase core
Embo J., 26, 2007
2GK7
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BU of 2gk7 by Molmil
Structural and Functional insights into the human Upf1 helicase core
Descriptor: PHOSPHATE ION, Regulator of nonsense transcripts 1
Authors:Cheng, Z, Muhlrad, D, Parker, R, Song, H.
Deposit date:2006-03-31
Release date:2007-01-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and functional insights into the human Upf1 helicase core
Embo J., 26, 2007
7UD6
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BU of 7ud6 by Molmil
Designed Enzyme SH3-588 (Catechol O-methyltransferase catalytic domain and Src homology 3 binding domain fusion)
Descriptor: POTASSIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Tyrosine-protein kinase Fyn,Catechol O-methyltransferase
Authors:Ongpipattanakul, C, Nair, S.K.
Deposit date:2022-03-18
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Designer installation of a substrate recruitment domain to tailor enzyme specificity.
Nat.Chem.Biol., 19, 2023
5VL4
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BU of 5vl4 by Molmil
Accidental minimum contact crystal lattice formed by a redesigned protein oligomer
Descriptor: T33-53H-B
Authors:Cannon, K.A, Cascio, D, Sawaya, M.R, Park, R, Boyken, S, King, N, Yeates, T.
Deposit date:2017-04-24
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering.
Protein Sci., 29, 2020
6X2A
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BU of 6x2a by Molmil
SARS-CoV-2 u1S2q 1-RBD Up Spike Protein Trimer
Descriptor: Spike glycoprotein
Authors:Henderson, R, Acharya, P.
Deposit date:2020-05-20
Release date:2020-05-27
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
6X29
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BU of 6x29 by Molmil
SARS-CoV-2 rS2d Down State Spike Protein Trimer
Descriptor: Spike glycoprotein
Authors:Henderson, R, Acharya, P.
Deposit date:2020-05-20
Release date:2020-05-27
Last modified:2020-10-21
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
5IIE
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BU of 5iie by Molmil
STRUCTURE OF THE UNLIGANDED ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3
Descriptor: antibody DH501 FabH chain, antibody DH501 light chain
Authors:Nicely, N.I, Haynes, B.F.
Deposit date:2016-03-01
Release date:2017-03-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.
Cell Rep, 18, 2017
5T4Z
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BU of 5t4z by Molmil
STRUCTURE OF THE ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3 WITH FREE MAN9 GLYCAN
Descriptor: CALCIUM ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, antibody DH501 Fab heavy chain, ...
Authors:Nicely, N.I, Haynes, B.F.
Deposit date:2016-08-30
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.991 Å)
Cite:Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.
Cell Rep, 18, 2017
5DD5
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BU of 5dd5 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
Descriptor: ANTI-HIV ANTIBODY DH570.9 FAB HEAVY CHAIN
Authors:Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
Deposit date:2015-08-24
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
5KG9
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BU of 5kg9 by Molmil
Crystal structure of the gp120 v2 antibody RE505-22 Fab from IGH- and IGK-humanized mouse
Descriptor: Antibody RE505-22 Fab heavy chain, Antibody RE505-22 Fab light chain
Authors:Nicely, N.I.
Deposit date:2016-06-13
Release date:2017-01-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice.
J. Immunol., 198, 2017
7TC5
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BU of 7tc5 by Molmil
All Phe-Azurin variant - F15Y
Descriptor: Azurin, COPPER (II) ION, NITRATE ION, ...
Authors:Fedoretz-Maxwell, B.P, Worrall, L.J, Strynadka, N.C.J, Warren, J.J.
Deposit date:2021-12-22
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins.
Inorg.Chem., 61, 2022
7TC6
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BU of 7tc6 by Molmil
All Phe-Azurin variant - F15W
Descriptor: Azurin, COPPER (II) ION, NITRATE ION
Authors:Fedoretz-Maxwell, B.P, Worrall, L.J, Strynadka, N.C.J, Warren, J.J.
Deposit date:2021-12-22
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins.
Inorg.Chem., 61, 2022
4ZK7
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BU of 4zk7 by Molmil
Crystal structure of rescued two-component self-assembling tetrahedral cage T33-31
Descriptor: Chorismate mutase, Divalent-cation tolerance protein CutA
Authors:Liu, Y, Cascio, D, Sawaya, M.R, Bale, J, Collazo, M.J, Park, R, King, N, Baker, D, Yeates, T.
Deposit date:2015-04-30
Release date:2015-07-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression.
Protein Sci., 24, 2015
5CY5
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BU of 5cy5 by Molmil
Crystal structure of the T33-51H designed self-assembling protein tetrahedron
Descriptor: T33-51H-A, T33-51H-B
Authors:Cannon, K.A, Cascio, D, Park, R, Boyken, S, King, N, Yeates, T.O.
Deposit date:2015-07-30
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering.
Protein Sci., 29, 2020
6XRJ
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BU of 6xrj by Molmil
Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
Descriptor: DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
Authors:Manne, K, Nicely, N.I, Acharya, P.
Deposit date:2020-07-13
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021

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