5U94
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![BU of 5u94 by Molmil](/molmil-images/mine/5u94) | Crystal structure of the Mycobacterium tuberculosis PASTA kinase PknB in complex with the potential theraputic kinase inhibitor GSK690693. | Descriptor: | 4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-piperidin-3-ylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3 -yn-2-ol, GLYCEROL, MAGNESIUM ION, ... | Authors: | Wlodarchak, N, Satyshur, K, Striker, R. | Deposit date: | 2016-12-15 | Release date: | 2017-12-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | In Silico Screen and Structural Analysis Identifies Bacterial Kinase Inhibitors which Act with beta-Lactams To Inhibit Mycobacterial Growth. Mol. Pharm., 15, 2018
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2K6Q
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![BU of 2k6q by Molmil](/molmil-images/mine/2k6q) | LC3 p62 complex structure | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, p62_peptide from Sequestosome-1 | Authors: | Noda, N, Kumeta, H, Nakatogawa, H, Satoo, K, Adachi, W, Ishii, J, Fujioka, Y, Ohsumi, Y, Inagaki, F. | Deposit date: | 2008-07-17 | Release date: | 2008-09-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis of target recognition by ATG8/LC3 during selective autophagy To be Published
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4I5N
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![BU of 4i5n by Molmil](/molmil-images/mine/4i5n) | Structural mechanism of trimeric PP2A holoenzyme involving PR70: insight for Cdc6 dephosphorylation | Descriptor: | CALCIUM ION, MANGANESE (II) ION, Microcystin-LR (MCLR) bound form, ... | Authors: | Wlodarchak, N, Satyshur, K.A, Guo, F, Xing, Y. | Deposit date: | 2012-11-28 | Release date: | 2013-05-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation. Cell Res., 23, 2013
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4I5L
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![BU of 4i5l by Molmil](/molmil-images/mine/4i5l) | Structural mechanism of trimeric PP2A holoenzyme involving PR70: insight for Cdc6 dephosphorylation | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, MALONATE ION, ... | Authors: | Wlodarchak, N, Satyshur, K.A, Guo, F, Xing, Y. | Deposit date: | 2012-11-28 | Release date: | 2013-05-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation. Cell Res., 23, 2013
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3AXA
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![BU of 3axa by Molmil](/molmil-images/mine/3axa) | Crystal structure of afadin PDZ domain in complex with the C-terminal peptide from nectin-3 | Descriptor: | Afadin, Nectin-3 | Authors: | Fujiwara, Y, Goda, N, Narita, H, Satomura, K, Nakagawa, A, Sakisaka, T, Suzuki, M, Hiroaki, H. | Deposit date: | 2011-03-31 | Release date: | 2012-04-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Crystal structure of afadin PDZ domain-nectin-3 complex shows the structural plasticity of the ligand-binding site. Protein Sci., 24, 2015
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2EFS
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![BU of 2efs by Molmil](/molmil-images/mine/2efs) | Crystal structure of the C-terminal tropomyosin fragment with N- and C-terminal extensions of the leucine zipper at 2.0 angstroms resolution | Descriptor: | General control protein GCN4 and Tropomyosin 1 alpha chain | Authors: | Minakata, S, Nitanai, Y, Maeda, K, Oda, N, Wakabayashi, K, Maeda, Y. | Deposit date: | 2007-02-23 | Release date: | 2008-03-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Two crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule To be Published
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2EFR
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![BU of 2efr by Molmil](/molmil-images/mine/2efr) | Crystal structure of the c-terminal tropomyosin fragment with N- and C-terminal extensions of the leucine zipper at 1.8 angstroms resolution | Descriptor: | General control protein GCN4 and Tropomyosin 1 alpha chain | Authors: | Minakata, S, Nitanai, Y, Maeda, K, Oda, N, Wakabayashi, K, Maeda, Y. | Deposit date: | 2007-02-23 | Release date: | 2008-03-04 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Two crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule To be Published
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2D3E
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2RQH
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![BU of 2rqh by Molmil](/molmil-images/mine/2rqh) | Structure of GSPT1/ERF3A-PABC | Descriptor: | G1 to S phase transition 1, Polyadenylate-binding protein 1 | Authors: | Osawa, M, Nakanishi, T, Hosoda, N, Uchida, S, Hoshino, T, Katada, I, Shimada, I. | Deposit date: | 2009-05-08 | Release date: | 2010-05-26 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Eukaryotic Translation Termination Factor Gspt/Erf3 Recognizes Pabp with Chemical Exchange Using Two Overlapping Motifs To be Published
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1WR0
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![BU of 1wr0 by Molmil](/molmil-images/mine/1wr0) | Structural characterization of the MIT domain from human Vps4b | Descriptor: | SKD1 protein | Authors: | Takasu, H, Jee, J.G, Ohno, A, Goda, N, Fujiwara, K, Tochio, H, Shirakawa, M, Hiroaki, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-10-07 | Release date: | 2005-08-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural characterization of the MIT domain from human Vps4b Biochem.Biophys.Res.Commun., 334, 2005
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3VQF
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![BU of 3vqf by Molmil](/molmil-images/mine/3vqf) | Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein | Descriptor: | E3 ubiquitin-protein ligase LNX | Authors: | Akiyoshi, Y, Hamada, D, Goda, N, Tenno, T, Narita, H, Nakagawa, A, Furuse, M, Suzuki, M, Hiroaki, H. | Deposit date: | 2012-03-22 | Release date: | 2013-03-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.199 Å) | Cite: | Structural basis for down regulation of tight junction by PDZ-domain containing E3-Ubiquitin ligase To be Published
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8H1O
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![BU of 8h1o by Molmil](/molmil-images/mine/8h1o) | Cryo-EM structure of KpFtsZ-monobody double helical tube | Descriptor: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, Mb(Ec/KpFtsZ_S1) | Authors: | Fujita, J, Amesaka, H, Yoshizawa, T, Kuroda, N, Kamimura, N, Hara, M, Inoue, T, Namba, K, Tanaka, S, Matsumura, H. | Deposit date: | 2022-10-03 | Release date: | 2023-08-02 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.67 Å) | Cite: | Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody. Nat Commun, 14, 2023
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8IBN
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![BU of 8ibn by Molmil](/molmil-images/mine/8ibn) | Cryo-EM structure of KpFtsZ single filament | Descriptor: | Cell division protein FtsZ, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, POTASSIUM ION | Authors: | Fujita, J, Amesaka, H, Yoshizawa, T, Kuroda, N, Kamimura, N, Hibino, K, Konishi, T, Kato, Y, Hara, M, Inoue, T, Namba, K, Tanaka, S, Matsumura, H. | Deposit date: | 2023-02-10 | Release date: | 2023-08-02 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody. Nat Commun, 14, 2023
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2RPA
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![BU of 2rpa by Molmil](/molmil-images/mine/2rpa) | The solution structure of N-terminal domain of microtubule severing enzyme | Descriptor: | Katanin p60 ATPase-containing subunit A1 | Authors: | Iwaya, N, Kuwahara, Y, Unzai, S, Nagata, T, Tomii, K, Goda, N, Tochio, H, Shirakawa, M, Hiroaki, H. | Deposit date: | 2008-05-13 | Release date: | 2009-05-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | A common substrate recognition mode conserved between katanin P60 and VPS4 governs microtubule severing and membrane skeleton reorganization J.Biol.Chem., 285, 2010
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2RRE
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![BU of 2rre by Molmil](/molmil-images/mine/2rre) | Structure and function of the N-terminal nucleolin binding domain of nuclear valocine containing protein like 2 (NVL2) harboring a nucleolar localization signal | Descriptor: | Putative uncharacterized protein | Authors: | Fujiwara, Y, Fujiwara, K, Goda, N, Iwaya, N, Tenno, T, Shirakawa, M, Hiroaki, H. | Deposit date: | 2010-08-03 | Release date: | 2011-04-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and function of the N-terminal nucleolin binding domain of nuclear valosin-containing protein-like 2 (NVL2) harboring a nucleolar localization signal J.Biol.Chem., 286, 2011
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2RRI
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![BU of 2rri by Molmil](/molmil-images/mine/2rri) | NMR structure of vasoactive intestinal peptide in DPC Micelle | Descriptor: | Vasoactive intestinal peptide | Authors: | Umetsu, Y, Tenno, T, Goda, N, Shirakawa, M, Ikegami, T, Hiroaki, H. | Deposit date: | 2010-12-21 | Release date: | 2011-04-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural difference of vasoactive intestinal peptide in two distinct membrane-mimicking environments Biochim.Biophys.Acta, 1814, 2011
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2RRH
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![BU of 2rrh by Molmil](/molmil-images/mine/2rrh) | NMR structure of vasoactive intestinal peptide in Methanol | Descriptor: | VIP peptides | Authors: | Umetsu, Y, Tenno, T, Goda, N, Ikegami, T, Hiroaki, H. | Deposit date: | 2010-11-12 | Release date: | 2011-04-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural difference of vasoactive intestinal peptide in two distinct membrane-mimicking environments. Biochim.Biophys.Acta, 1814, 2011
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2RQG
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![BU of 2rqg by Molmil](/molmil-images/mine/2rqg) | Structure of GSPT1/ERF3A-PABC | Descriptor: | G1 to S phase transition 1, Polyadenylate-binding protein 1 | Authors: | Osawa, M, Nakanishi, T, Hosoda, N, Uchida, S, Hoshino, T, Katada, I, Shimada, I. | Deposit date: | 2009-05-08 | Release date: | 2010-05-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Eukaryotic Translation Termination Factor Gspt/Erf3 Recognizes Pabp with Chemical Exchange Using Two Overlapping Motifs To be Published
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2RRM
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![BU of 2rrm by Molmil](/molmil-images/mine/2rrm) | Interplay between phosphatidyl-inositol-phosphates and claudins upon binding to the 1st PDZ domain of zonula occludens 1 | Descriptor: | Tight junction protein ZO-1 | Authors: | Hiroaki, H, Satomura, K, Goda, N, Umetsu, Y, Taniguchi, R, Ikegami, T, Furuse, M. | Deposit date: | 2011-01-06 | Release date: | 2011-05-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | 1H, 13C, and 15N resonance assignment of the first PDZ domain of mouse ZO-1 Biomol.Nmr Assign., 5, 2011
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6KVP
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![BU of 6kvp by Molmil](/molmil-images/mine/6kvp) | S. aureus FtsZ in complex with 3-(1-(5-bromo-4-(4-(trifluoromethyl)phenyl)oxazol-2-yl)ethoxy)-2,6-difluorobenzamide (compound 2) | Descriptor: | 3-[(1R)-1-[5-bromanyl-4-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-yl]ethoxy]-2,6-bis(fluoranyl)benzamide, CALCIUM ION, Cell division protein FtsZ, ... | Authors: | Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S. | Deposit date: | 2019-09-05 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens. Sci Rep, 9, 2019
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1WLF
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![BU of 1wlf by Molmil](/molmil-images/mine/1wlf) | Structure of the N-terminal domain of PEX1 AAA-ATPase: Characterization of a putative adaptor-binding domain | Descriptor: | Peroxisome biogenesis factor 1, SULFATE ION | Authors: | Shiozawa, K, Maita, N, Tomii, K, Seto, A, Goda, N, Tochio, H, Akiyama, Y, Shimizu, T, Shirakawa, M, Hiroaki, H. | Deposit date: | 2004-06-25 | Release date: | 2004-09-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of the N-terminal Domain of PEX1 AAA-ATPase: CHARACTERIZATION OF A PUTATIVE ADAPTOR-BINDING DOMAIN J.Biol.Chem., 279, 2004
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6KVQ
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![BU of 6kvq by Molmil](/molmil-images/mine/6kvq) | S. aureus FtsZ in complex with BOFP (compound 3) | Descriptor: | CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S. | Deposit date: | 2019-09-05 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens. Sci Rep, 9, 2019
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7WH3
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![BU of 7wh3 by Molmil](/molmil-images/mine/7wh3) | Solution structure of human stomatin SPFH domain in a phosphate buffer | Descriptor: | Stomatin | Authors: | Kataoka, K, Tenno, T, Goda, N, Hibino, E, Hiroaki, H. | Deposit date: | 2021-12-29 | Release date: | 2022-06-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A cryptic phosphate-binding pocket on the SPFH domain of human stomatin that regulates a novel fibril-like self-assembly Curr Res Struct Biol, 4, 2022
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6LL5
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![BU of 6ll5 by Molmil](/molmil-images/mine/6ll5) | Crystal structure of KpFtsZ (residues 11-316) | Descriptor: | Cell division protein FtsZ, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE | Authors: | Yoshizawa, T, Fujita, J, Terakado, H, Ozawa, M, Kuroda, N, Tanaka, S, Uehara, R, Matsumura, H. | Deposit date: | 2019-12-21 | Release date: | 2020-02-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structures of the cell-division protein FtsZ from Klebsiella pneumoniae and Escherichia coli. Acta Crystallogr.,Sect.F, 76, 2020
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6LL6
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![BU of 6ll6 by Molmil](/molmil-images/mine/6ll6) | Crsyal structure of EcFtsZ (residues 11-316) | Descriptor: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | Authors: | Yoshizawa, T, Fujita, J, Terakada, H, Ozawa, M, Kuroda, N, Tanaka, S, Uehara, R, Matsumura, H. | Deposit date: | 2019-12-21 | Release date: | 2020-02-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of the cell-division protein FtsZ from Klebsiella pneumoniae and Escherichia coli. Acta Crystallogr.,Sect.F, 76, 2020
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