6KVP

S. aureus FtsZ in complex with 3-(1-(5-bromo-4-(4-(trifluoromethyl)phenyl)oxazol-2-yl)ethoxy)-2,6-difluorobenzamide (compound 2)

Summary for 6KVP

Entry DOI	10.2210/pdb6kvp/pdb
Descriptor	Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (5 entities in total)
Functional Keywords	gtpase, protein-inhibitor complex, hydrolase
Biological source	Staphylococcus aureus
Total number of polymer chains	1
Total formula weight	32827.51
Authors	Ferrer-Gonzalez, E.,Fujita, J.,Yoshizawa, T.,Nelson, J.M.,Pilch, A.J.,Hillman, E.,Ozawa, M.,Kuroda, N.,Parhi, A.K.,LaVoie, E.J.,Matsumura, H.,Pilch, D.S. (deposition date: 2019-09-05, release date: 2020-01-15, Last modification date: 2023-11-22)
Primary citation	Ferrer-Gonzalez, E.,Fujita, J.,Yoshizawa, T.,Nelson, J.M.,Pilch, A.J.,Hillman, E.,Ozawa, M.,Kuroda, N.,Al-Tameemi, H.M.,Boyd, J.M.,LaVoie, E.J.,Matsumura, H.,Pilch, D.S. Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens. Sci Rep, 9:20092-20092, 2019 Cited by PubMed: 31882782 DOI: 10.1038/s41598-019-56557-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation