3AXA

Crystal structure of afadin PDZ domain in complex with the C-terminal peptide from nectin-3

Summary for 3AXA

Entry DOI	10.2210/pdb3axa/pdb
Descriptor	Afadin, Nectin-3 (2 entities in total)
Functional Keywords	pdz domain, af-6, fusion protein, cell adhesion
Biological source	Mus musculus (mouse, mouse) More
Cellular location	Cell membrane ; Single-pass membrane protein : Q9JLB9
Total number of polymer chains	2
Total formula weight	22209.42
Authors	Fujiwara, Y.,Goda, N.,Narita, H.,Satomura, K.,Nakagawa, A.,Sakisaka, T.,Suzuki, M.,Hiroaki, H. (deposition date: 2011-03-31, release date: 2012-04-25, Last modification date: 2023-11-01)
Primary citation	Fujiwara, Y.,Goda, N.,Tamashiro, T.,Narita, H.,Satomura, K.,Tenno, T.,Nakagawa, A.,Oda, M.,Suzuki, M.,Sakisaka, T.,Takai, Y.,Hiroaki, H. Crystal structure of afadin PDZ domain-nectin-3 complex shows the structural plasticity of the ligand-binding site. Protein Sci., 24:376-385, 2015 Cited by PubMed: 25534554 DOI: 10.1002/pro.2628 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.78 Å)

Structure validation