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2EFS

Crystal structure of the C-terminal tropomyosin fragment with N- and C-terminal extensions of the leucine zipper at 2.0 angstroms resolution

Summary for 2EFS
Entry DOI10.2210/pdb2efs/pdb
DescriptorGeneral control protein GCN4 and Tropomyosin 1 alpha chain (2 entities in total)
Functional Keywordsdestabilizing cluster, hydrophobic core, contractile protein
Biological sourceSaccharomyces cerevisiae (baker's yeast, rabbit)
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Cellular locationCytoplasm, cytoskeleton: P58772
Total number of polymer chains4
Total formula weight73354.78
Authors
Minakata, S.,Nitanai, Y.,Maeda, K.,Oda, N.,Wakabayashi, K.,Maeda, Y. (deposition date: 2007-02-23, release date: 2008-03-04, Last modification date: 2023-10-25)
Primary citationMinakata, S.,Nitanai, Y.,Maeda, K.,Oda, N.,Wakabayashi, K.,Maeda, Y.
Two crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule
To be Published,
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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