1GWZ
 
 | | CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE PROTEIN TYROSINE PHOSPHATASE SHP-1 | | 分子名称: | SHP-1 | | 著者 | Yang, J, Liang, X, Niu, T, Meng, W, Zhao, Z, Zhou, G.W. | | 登録日 | 1998-08-22 | | 公開日 | 1999-08-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 273, 1998
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5DAB
 | | Crystal structure of FTO-IN115 | | 分子名称: | 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase FTO, CHLORIDE ION, ... | | 著者 | Chai, J, Zhou, B, Liu, W, Han, Z, Niu, T. | | 登録日 | 2015-08-19 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of FTO-IN115
To Be Published
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1FPR
 | | CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN THE CATALYTIC DOMAIN OF SHP-1 AND AN IN VITRO PEPTIDE SUBSTRATE PY469 DERIVED FROM SHPS-1. | | 分子名称: | PEPTIDE PY469, PROTEIN-TYROSINE PHOSPHATASE 1C | | 著者 | Yang, J, Cheng, Z, Niu, Z, Zhao, Z.J, Zhou, G.W. | | 登録日 | 2000-08-31 | | 公開日 | 2001-03-07 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 275, 2000
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7F7W
 | | JAK2-JH2 | | 分子名称: | 2-((1-(2-fluoro-4-((4-(1-isopropyl-1H-pyrazol-4-yl)-5-methylpyrimidin-2-yl)amino)phenyl)piperidin-4-yl)(methyl)amino)ethan-1-ol, Tyrosine-protein kinase JAK2 | | 著者 | Niu, L. | | 登録日 | 2021-06-30 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Preclinical studies of Flonoltinib Maleate, a novel JAK2/FLT3 inhibitor, in treatment of JAK2 V617F -induced myeloproliferative neoplasms.
Blood Cancer J, 12, 2022
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5H3D
 | | Helical structure of membrane tubules decorated by ACAP1 (BARPH doamin) protein by cryo-electron microscopy and MD simulation | | 分子名称: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 | | 著者 | Chan, C, Pang, X.Y, Zhang, Y, Sun, F, Fan, J. | | 登録日 | 2016-10-22 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (14 Å) | | 主引用文献 | ACAP1 assembles into an unusual protein lattice for membrane deformation through multiple stages.
Plos Comput.Biol., 15, 2019
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3LFM
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6JC3
 | | The Cryo-EM structure of nucleoprotein-RNA complex of Newcastle disease virus | | 分子名称: | Nucleocapsid, polyU | | 著者 | Song, X, Shan, H, Zhu, Y, Ding, W, Ouyang, S, Shen, Q.T, Liu, Z.J. | | 登録日 | 2019-01-28 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Self-capping of nucleoprotein filaments protects the Newcastle disease virus genome.
Elife, 8, 2019
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7CYC
 | | Cryo-EM structures of Alphacoronavirus spike glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Song, X, Shi, Y, Ding, W, Liu, Z.J, Peng, G. | | 登録日 | 2020-09-03 | | 公開日 | 2020-12-23 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes.
Nat Commun, 12, 2021
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7CYD
 | | Cryo-EM structures of Alphacoronavirus spike glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Song, X, Shi, Y, Ding, W, Liu, Z.J, Peng, G. | | 登録日 | 2020-09-03 | | 公開日 | 2020-12-23 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | | 主引用文献 | Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes.
Nat Commun, 12, 2021
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