1FPR
CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN THE CATALYTIC DOMAIN OF SHP-1 AND AN IN VITRO PEPTIDE SUBSTRATE PY469 DERIVED FROM SHPS-1.
Summary for 1FPR
Entry DOI | 10.2210/pdb1fpr/pdb |
Descriptor | PROTEIN-TYROSINE PHOSPHATASE 1C, PEPTIDE PY469 (2 entities in total) |
Functional Keywords | protein tyrosine phosphatase, substrate specificity, residue shift, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P29350 |
Total number of polymer chains | 2 |
Total formula weight | 33793.93 |
Authors | Yang, J.,Cheng, Z.,Niu, Z.,Zhao, Z.J.,Zhou, G.W. (deposition date: 2000-08-31, release date: 2001-03-07, Last modification date: 2021-11-03) |
Primary citation | Yang, J.,Cheng, Z.,Niu, T.,Liang, X.,Zhao, Z.J.,Zhou, G.W. Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1. J.Biol.Chem., 275:4066-4071, 2000 Cited by PubMed: 10660565DOI: 10.1074/jbc.275.6.4066 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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