4XI5
| gHgL of varicella-zoster virus in complex with human neutralizing antibodies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... | 著者 | Xing, Y. | 登録日 | 2015-01-06 | 公開日 | 2015-05-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL. Proc.Natl.Acad.Sci.USA, 112, 2015
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8UF5
| Catalytic domain of GtfB in complex with inhibitor G43 | 分子名称: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | 著者 | Schormann, N, Deivanayagam, C, Velu, S. | 登録日 | 2023-10-03 | 公開日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence. Sci Rep, 7, 2017
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3MJW
| PI3 Kinase gamma with a benzofuranone inhibitor | 分子名称: | (2Z)-4,6-dihydroxy-2-[(8-methoxy-1,2,3,4-tetrahydropyrazino[1,2-a]indol-10-yl)methylidene]-1-benzofuran-3(2H)-one, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 著者 | Bard, J, Svenson, K. | 登録日 | 2010-04-13 | 公開日 | 2010-06-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | 5-Ureidobenzofuranone indoles as potent and efficacious inhibitors of PI3 kinase-alpha and mTOR for the treatment of breast cancer. Bioorg.Med.Chem.Lett., 20, 2010
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4KG9
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5IWL
| CD47-diabody complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5F9 diabody, Leukocyte surface antigen CD47, ... | 著者 | Di, W, Jude, K.M, Garcia, K.C. | 登録日 | 2016-03-22 | 公開日 | 2016-06-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. J.Clin.Invest., 126, 2016
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5VOD
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5VOB
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5VOC
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6MCY
| Crystal structure of mouse Bak | 分子名称: | 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, FORMIC ACID | 著者 | Brouwer, J.M, Czabotar, P.E, Colman, P.M. | 登録日 | 2018-09-03 | 公開日 | 2019-09-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.748 Å) | 主引用文献 | A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis. Nat.Chem.Biol., 15, 2019
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2LBN
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2LBH
| Solution Structure of the Dimeric Form of a Unliganded Bovine Neurophysin, Minimized Average Structure | 分子名称: | Neurophysin 1 | 著者 | Lee, H, Naik, M, Nguyen, T, Bracken, C, Breslow, E. | 登録日 | 2011-03-31 | 公開日 | 2012-04-04 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis of the Dimerization-Induced Increase in Neurophysin-Hormone Affinity: Interplay of Inter-Domain and Inter-Subunit Interactions To be Published
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