8UF5

Catalytic domain of GtfB in complex with inhibitor G43

Summary for 8UF5

• Entry DOI: 10.2210/pdb8uf5/pdb
• Related: 8FG8
• Descriptor: Glucosyltransferase-I, CALCIUM ION, N-(2-carbamoylphenyl)-5-nitro-1-benzothiophene-2-carboxamide, ... (8 entities in total)
• Functional Keywords: gtfb, gtf-i, catalytic domain, inhibitor, transferase-inhibitor complex, cell adhesion
• Biological source: Streptococcus mutans
• Total number of polymer chains: 2
• Total formula weight: 196980.93

Authors

Schormann, N.,Deivanayagam, C.,Velu, S. (deposition date: 2023-10-03, release date: 2023-10-18)

• Primary citation: Zhang, Q.,Nijampatnam, B.,Hua, Z.,Nguyen, T.,Zou, J.,Cai, X.,Michalek, S.M.,Velu, S.E.,Wu, H.; Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence.; Sci Rep, 7:5974-, 2017; PubMed: 28729722; DOI: 10.1177/00220345580370060901

Experimental method

X-RAY DIFFRACTION (2.5 Å)