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2KHH
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BU of 2khh by Molmil
Structural requirements for the UBA domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation Tho complex component Hpr1 and nucleoporin FxFG repeats
Descriptor: FxFG, mRNA export factor MEX67
Authors:Hobeika, M, Brockmann, C, Gruessing, F, Neuhaus, D, Divita, G, Stewart, M, Dargemont, C.
Deposit date:2009-04-06
Release date:2009-05-12
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structural requirements for the ubiquitin-associated domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation THO complex component Hpr1 and nucleoporin FXFG repeats
J.Biol.Chem., 284, 2009
2L5G
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BU of 2l5g by Molmil
Co-ordinates and 1H, 13C and 15N chemical shift assignments for the complex of GPS2 53-90 and SMRT 167-207
Descriptor: G protein pathway suppressor 2, Putative uncharacterized protein NCOR2
Authors:Oberoi, J, Yang, J, Neuhaus, D, Schwabe, J.W.R.
Deposit date:2010-11-01
Release date:2011-02-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.
Nat.Struct.Mol.Biol., 18, 2011
2LHN
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BU of 2lhn by Molmil
RNA-binding zinc finger protein
Descriptor: Nuclear polyadenylated RNA-binding protein NAB2, ZINC ION
Authors:Brockmann, C, Neuhaus, D, Stewart, M.
Deposit date:2011-08-12
Release date:2012-06-27
Method:SOLUTION NMR
Cite:Structural Basis for Polyadenosine-RNA Binding by Nab2 Zn Fingers and Its Function in mRNA Nuclear Export.
Structure, 20, 2012
1MRB
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BU of 1mrb by Molmil
THREE-DIMENSIONAL STRUCTURE OF RABBIT LIVER CD7 METALLOTHIONEIN-2A IN AQUEOUS SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE
Descriptor: CADMIUM ION, CD7 METALLOTHIONEIN-2A
Authors:Braun, W, Arseniev, A, Schultze, P, Woergoetter, E, Wagner, G, Vasak, M, Kaegi, J.H.R, Wuthrich, K.
Deposit date:1990-05-14
Release date:1991-04-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance.
J.Mol.Biol., 201, 1988
8A58
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BU of 8a58 by Molmil
X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W
Descriptor: E3 ubiquitin-protein ligase TRIM21, Ubiquitin-conjugating enzyme E2 W, ZINC ION
Authors:James, L.C, Kiss, L.
Deposit date:2022-06-14
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
Nat Commun, 14, 2023
2MRB
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BU of 2mrb by Molmil
THREE-DIMENSIONAL STRUCTURE OF RABBIT LIVER CD-7 METALLOTHIONEIN-2A IN AQUEOUS SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE
Descriptor: CADMIUM ION, CD7 METALLOTHIONEIN-2A
Authors:Braun, W, Arseniev, A, Schultze, P, Woergoetter, E, Wagner, G, Vasak, M, Kaegi, J.H.R, Wuthrich, K.
Deposit date:1990-05-14
Release date:1991-04-15
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance.
J.Mol.Biol., 201, 1988
6QH5
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BU of 6qh5 by Molmil
AP2 clathrin adaptor mu2T156-phosphorylated core in closed conformation
Descriptor: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6TX1
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BU of 6tx1 by Molmil
HPF1 from Nematostella vectensis
Descriptor: Predicted protein
Authors:Suskiewicz, M.J, Ahel, I.
Deposit date:2020-01-13
Release date:2020-02-19
Last modified:2020-04-08
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation.
Nature, 579, 2020
6TVH
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BU of 6tvh by Molmil
Selenomethionine-substituted HPF1 from Nematostella vectensis
Descriptor: Predicted protein
Authors:Ariza, A.
Deposit date:2020-01-09
Release date:2020-02-19
Last modified:2020-04-08
Method:X-RAY DIFFRACTION (2.651 Å)
Cite:HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation.
Nature, 579, 2020
6TX2
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BU of 6tx2 by Molmil
Human HPF1
Descriptor: Histone PARylation factor 1, SODIUM ION
Authors:Suskiewicz, M.J, Ahel, I.
Deposit date:2020-01-13
Release date:2020-02-19
Last modified:2020-04-08
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation.
Nature, 579, 2020
5OLM
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BU of 5olm by Molmil
TRIM21
Descriptor: E3 ubiquitin-protein ligase TRIM21, ZINC ION
Authors:James, L.C.
Deposit date:2017-07-28
Release date:2018-04-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.
Elife, 7, 2018
3CW1
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BU of 3cw1 by Molmil
Crystal Structure of Human Spliceosomal U1 snRNP
Descriptor: Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, ...
Authors:Pomeranz Krummel, D.A, Oubridge, C, Leung, A.K, Li, J, Nagai, K.
Deposit date:2008-04-21
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (5.493 Å)
Cite:Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution.
Nature, 458, 2009
6TX3
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BU of 6tx3 by Molmil
HPF1 bound to catalytic fragment of PARP2
Descriptor: 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Histone PARylation factor 1, Poly [ADP-ribose] polymerase 2,Poly [ADP-ribose] polymerase 2
Authors:Suskiewicz, M.J, Ahel, I.
Deposit date:2020-01-13
Release date:2020-02-19
Last modified:2020-04-08
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation.
Nature, 579, 2020
1E6I
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BU of 1e6i by Molmil
Bromodomain from GCN5 complexed with acetylated H4 peptide
Descriptor: HISTONE H4, TRANSCRIPTIONAL ACTIVATOR GCN5
Authors:Owen, D.J, Travers, A.A, Evans, P.R.
Deposit date:2000-08-18
Release date:2000-11-24
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The Structural Basis for the Recognition of Acetylated Histone H4 by the Bromodomain of Histone Acetyltransferase Gcn5P
Embo J., 19, 2000
2V75
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BU of 2v75 by Molmil
N-terminal domain of Nab2
Descriptor: NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN NAB2
Authors:Grant, R.P, Marshall, N.J, Stewart, M.
Deposit date:2007-07-26
Release date:2008-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the N-Terminal Mlp1-Binding Domain of the Saccharomyces Cerevisiae Mrna-Binding Protein, Nab2.
J.Mol.Biol., 376, 2008
2XTE
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BU of 2xte by Molmil
Structure of the TBL1 tetramerisation domain
Descriptor: F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTC
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BU of 2xtc by Molmil
Structure of the TBL1 tetramerisation domain
Descriptor: F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTD
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BU of 2xtd by Molmil
Structure of the TBL1 tetramerisation domain
Descriptor: TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
1HCQ
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BU of 1hcq by Molmil
THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS
Descriptor: DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP*CP*CP*T P*G)-3'), DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP*CP*CP*T P*G)-3'), PROTEIN (ESTROGEN RECEPTOR), ...
Authors:Schwabe, J.W.R, Chapman, L, Finch, J.T, Rhodes, D.
Deposit date:1995-01-04
Release date:1995-11-23
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements.
Cell(Cambridge,Mass.), 75, 1993
6QH6
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BU of 6qh6 by Molmil
AP2 clathrin adaptor core with two cargo peptides in open+ conformation
Descriptor: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Last modified:2022-12-07
Method:X-RAY DIFFRACTION (5 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6QH7
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BU of 6qh7 by Molmil
AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation
Descriptor: ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ...
Authors:Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
7O06
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BU of 7o06 by Molmil
Crystal structure of the N-terminal domain of CEP164(1-109) bound to camelid nanobody 10Z
Descriptor: Camelid nanobody 10Z, Centrosomal protein of 164 kDa, SULFATE ION
Authors:e Silva, I.R, van Breugel, M.
Deposit date:2021-03-25
Release date:2021-09-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
7NWJ
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BU of 7nwj by Molmil
Solution NMR structure of the N-terminal domain of CEP164 (1-109)
Descriptor: Centrosomal protein of 164 kDa
Authors:van Breugel, M, Rutherford, T.J.
Deposit date:2021-03-16
Release date:2021-09-15
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
7O0S
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BU of 7o0s by Molmil
Crystal structure of the N-terminal domain of CEP164(1-109) bound to camelid nanobody 36Z
Descriptor: Centrosomal protein of 164 kDa, Nanobody 36Z
Authors:e Silva, I.R, van Breugel, M.
Deposit date:2021-03-26
Release date:2021-09-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
7O3B
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BU of 7o3b by Molmil
Crystal structure of the TTBK2-CEP164 complex bound to a camelid nanobody
Descriptor: Nanobody 36Z, Tau-tubulin kinase 2,Centrosomal protein of 164 kDa
Authors:e Silva, I.R, van Breugel, M.
Deposit date:2021-04-01
Release date:2021-09-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
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