6TX2
Human HPF1
Summary for 6TX2
| Entry DOI | 10.2210/pdb6tx2/pdb |
| Descriptor | Histone PARylation factor 1, SODIUM ION (3 entities in total) |
| Functional Keywords | parp1, parp2, adp-ribosylation, serine adp-ribosylation, c4orf27, protein binding |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 36776.02 |
| Authors | Suskiewicz, M.J.,Ahel, I. (deposition date: 2020-01-13, release date: 2020-02-19, Last modification date: 2020-04-08) |
| Primary citation | Suskiewicz, M.J.,Zobel, F.,Ogden, T.E.H.,Fontana, P.,Ariza, A.,Yang, J.C.,Zhu, K.,Bracken, L.,Hawthorne, W.J.,Ahel, D.,Neuhaus, D.,Ahel, I. HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation. Nature, 579:598-602, 2020 Cited by PubMed: 32028527DOI: 10.1038/s41586-020-2013-6 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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