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6SH2
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BU of 6sh2 by Molmil
Crystal structure of human neprilysin E584D in complex with C-type natriuretic peptide.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type natriuretic peptide fragment (CNP), CHLORIDE ION, ...
著者Moss, S, Subramanian, V, Acharya, K.R.
登録日2019-08-05
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of peptide-bound neprilysin reveals key binding interactions.
Febs Lett., 594, 2020
6SH1
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BU of 6sh1 by Molmil
Crystal structure of substrate-free human neprilysin E584D.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Neprilysin, ...
著者Moss, S, Subramanian, V, Acharya, K.R.
登録日2019-08-05
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of peptide-bound neprilysin reveals key binding interactions.
Febs Lett., 594, 2020
6GID
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BU of 6gid by Molmil
High resolution crystal structure of substrate-free human neprilysin
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Moss, S, Subramanian, V, Acharya, K.R.
登録日2018-05-10
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High resolution crystal structure of substrate-free human neprilysin.
J. Struct. Biol., 204, 2018
1GNU
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BU of 1gnu by Molmil
GABA(A) receptor associated protein GABARAP
分子名称: GABARAP, NICKEL (II) ION
著者Knight, D, Harris, R, Moss, S, Driscoll, P.C, Keep, N.H.
登録日2001-10-09
公開日2001-12-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The X-Ray Crystal Structure and Putative Ligand-Derived Peptide Binding Properties of Gamma-Aminobutyric Acid Receptor Type a Receptor-Associated Protein
J.Biol.Chem., 277, 2002
8OXG
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BU of 8oxg by Molmil
Crystal structure of human methionine aminopeptidase-2 complexed with (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl N-(trans-4-aminocyclohexyl)carbamate
分子名称: MANGANESE (II) ION, Methionine aminopeptidase 2, [(1~{R},2~{S},3~{S},4~{R})-2-methoxy-4-methyl-3-[(2~{R},3~{S})-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-4-oxidanyl-cyclohexyl] ~{N}-(4-azanylcyclohexyl)carbamate
著者Moss, S, Cornelius, P.
登録日2023-05-02
公開日2024-04-10
実験手法X-RAY DIFFRACTION (1.731 Å)
主引用文献Pharmacological Characterization of SDX-7320/Evexomostat: a Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-Tumor and Anti-Metastatic Activity.
Mol.Cancer Ther., 2024
7Z9P
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BU of 7z9p by Molmil
The novel DNA binding mechanism of ridinilazole, a precision Clostridiodes difficile antibiotic
分子名称: DNA (5'-D(P*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G*(RID))-3'), Ridinilazole, SODIUM ION, ...
著者Mason, S, Leonard, P.M.
登録日2022-03-21
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic.
Antimicrob.Agents Chemother., 67, 2023
6RU5
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BU of 6ru5 by Molmil
human complement C3 in complex with the hC3Nb1 nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jensen, R.K, Andersen, G.R.
登録日2019-05-27
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
6RU3
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BU of 6ru3 by Molmil
Crystal structure of the FP specific nanobody hFPNb1
分子名称: hFP1Nb1
著者Mazarakis, S.M.M, Pedersen, D.V, Laursen, N.S, Andersen, G.R.
登録日2019-05-27
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
6RUR
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BU of 6rur by Molmil
Structure of the SCIN stabilized C3bBb convertase bound to properdin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, ...
著者Pedersen, D.V, Gadeberg, T.A.F, Andersen, G.R.
登録日2019-05-29
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
6RUS
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BU of 6rus by Molmil
Structure of a functional properdin monomer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, SULFATE ION, ...
著者Pedersen, D.V, Andersen, G.R.
登録日2019-05-29
公開日2019-08-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
6RUV
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BU of 6ruv by Molmil
Structure of the SCIN stabilized C3bBb convertase bound to Properdin and a the non-inhibitory nanobody hFPNb1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, ...
著者Pedersen, D.V, Andersen, G.R.
登録日2019-05-29
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (6.15 Å)
主引用文献Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
6RV6
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BU of 6rv6 by Molmil
Structure of properdin lacking TSR3 based on anomalous data
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, alpha-D-mannopyranose, ...
著者Pedersen, D.V, Andersen, G.R.
登録日2019-05-31
公開日2019-08-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.507 Å)
主引用文献Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
6SEJ
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BU of 6sej by Molmil
Structure of a functional monomeric properdin lacking TSR3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, alpha-D-mannopyranose, ...
著者Pedersen, D.V, Andersen, G.R.
登録日2019-07-30
公開日2019-08-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.501 Å)
主引用文献Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019

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