1R5H
| Crystal Structure of MetAP2 complexed with A320282 | 分子名称: | MANGANESE (II) ION, Methionine aminopeptidase 2, N'-(2S,3R)-3-AMINO-4-CYCLOHEXYL-2-HYDROXY-BUTANO-N-(4-METHYLPHENYL)HYDRAZIDE | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | 登録日 | 2003-10-10 | 公開日 | 2004-10-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2. Bioorg.Med.Chem.Lett., 14, 2004
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1R5G
| Crystal Structure of MetAP2 complexed with A311263 | 分子名称: | (2S,3R)-3-AMINO-2-HYDROXY-5-(ETHYLSULFANYL)PENTANOYL-((S)-(-)-(1-NAPHTHYL)ETHYL)AMIDE, MANGANESE (II) ION, Methionine aminopeptidase 2 | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | 登録日 | 2003-10-10 | 公開日 | 2004-10-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2. Bioorg.Med.Chem.Lett., 14, 2004
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1R58
| Crystal Structure of MetAP2 complexed with A357300 | 分子名称: | MANGANESE (II) ION, Methionine aminopeptidase 2, N'-((2S,3R)-3-AMINO-2-HYDROXY-5-(ISOPROPYLSULFANYL)PENTANOYL)-N-3-CHLOROBENZOYL HYDRAZIDE | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Ericken, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | 登録日 | 2003-10-09 | 公開日 | 2004-10-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2. Bioorg.Med.Chem.Lett., 14, 2004
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1N9U
| Differences and Similarities in Solution Structures of Angiotensin I & II: Implication for Structure-Function Relationship | 分子名称: | Angiotensin I | 著者 | Spyroulias, G.A, Nikolakopoulou, P, Tzakos, A, Gerothanassis, I.P, Magafa, V, Manessi-Zoupa, E, Cordopatis, P. | 登録日 | 2002-11-26 | 公開日 | 2003-07-29 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Comparison of the solution structures of angiotensin I & II. Implication for structure-function relationship. Eur.J.Biochem., 270, 2003
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1N9V
| Differences and Similarities in Solution Structures of Angiotensin I & II: Implication for Structure-Function Relationship. | 分子名称: | Angiotensin II | 著者 | Spyroulias, G.A, Nikolakopoulou, P, Tzakos, A, Gerothanassis, I.P, Magafa, V, Manessi-Zoupa, E, Cordopatis, P. | 登録日 | 2002-11-26 | 公開日 | 2003-07-29 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Comparison of the solution structures of angiotensin I & II. Implication for structure-function relationship. Eur.J.Biochem., 270, 2003
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8GMH
| Crystal Structure of the ternary complex of TelA-LXG, LapA3, and LapA4 | 分子名称: | 1,2-ETHANEDIOL, LXG domain-containing protein, LapA3, ... | 著者 | Klein, T.A, Shah, P.Y, Gkragkopoulou, P, Grebenc, D.W, Kim, Y, Whitney, J.C. | 登録日 | 2023-03-25 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of a tripartite protein complex that targets toxins to the type VII secretion system. Proc.Natl.Acad.Sci.USA, 121, 2024
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1YW8
| h-MetAP2 complexed with A751277 | 分子名称: | 2-[(PHENYLSULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2 | 著者 | Park, C.H. | 登録日 | 2005-02-17 | 公開日 | 2006-02-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding. J.Med.Chem., 49, 2006
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1YW7
| h-MetAP2 complexed with A444148 | 分子名称: | 5-METHYL-2-[(PHENYLSULFONYL)AMINO]BENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2 | 著者 | Park, C.H. | 登録日 | 2005-02-17 | 公開日 | 2006-02-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding. J.Med.Chem., 49, 2006
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1YW9
| h-MetAP2 complexed with A849519 | 分子名称: | 2-[({2-[(1Z)-3-(DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2 | 著者 | Park, C.H. | 登録日 | 2005-02-17 | 公開日 | 2006-02-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding. J.Med.Chem., 49, 2006
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2EA2
| h-MetAP2 complexed with A773812 | 分子名称: | 3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2 | 著者 | Park, C.H. | 登録日 | 2007-01-30 | 公開日 | 2008-02-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids Bioorg.Med.Chem.Lett., 17, 2007
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2EA4
| h-MetAP2 complexed with A797859 | 分子名称: | 2-(2-AMINOETHOXY)-3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}BENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2 | 著者 | Park, C.H. | 登録日 | 2007-01-30 | 公開日 | 2008-02-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids Bioorg.Med.Chem.Lett., 17, 2007
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2GA2
| h-MetAP2 complexed with A193400 | 分子名称: | 5-BROMO-2-{[(4-CHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2 | 著者 | Park, C. | 登録日 | 2006-03-07 | 公開日 | 2007-03-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties. Bioorg.Med.Chem.Lett., 16, 2006
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3T9N
| Crystal structure of a membrane protein | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Small-conductance mechanosensitive channel | 著者 | Yang, M, Zhang, X, Ge, J, Wang, J. | 登録日 | 2011-08-03 | 公開日 | 2012-10-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.456 Å) | 主引用文献 | Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance Proc.Natl.Acad.Sci.USA, 109, 2012
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1UV5
| GLYCOGEN SYNTHASE KINASE 3 BETA COMPLEXED WITH 6-BROMOINDIRUBIN-3'-OXIME | 分子名称: | 6-BROMOINDIRUBIN-3'-OXIME, CHLORIDE ION, COBALT (II) ION, ... | 著者 | Dajani, R, Pearl, L.H, Roe, S.M. | 登録日 | 2004-01-14 | 公開日 | 2004-01-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Gsk-3-Selective Inhibitors Derived from Tyrian Purple Indurubins Chem.Biol., 10, 2003
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1K24
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6TH4
| Tubulin-inhibitor complex | 分子名称: | 1,2,3,9-tetramethoxy-6-methylidene-5~{H}-cyclohepta[a]naphthalen-8-one, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Varela, P.F, Gigant, B. | 登録日 | 2019-11-18 | 公開日 | 2021-12-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.121 Å) | 主引用文献 | B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner Acs Omega, 7, 2022
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6SEQ
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7N4T
| Low conductance mechanosensitive channel YnaI | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Low conductance mechanosensitive channel YnaI | 著者 | Catalano, C, Ben-Hail, D, Qiu, W, des Georges, A, Guo, Y. | 登録日 | 2021-06-04 | 公開日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Cryo-EM Structure of Mechanosensitive Channel YnaI Using SMA2000: Challenges and Opportunities. Membranes (Basel), 11, 2021
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2QLU
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3UDC
| Crystal structure of a membrane protein | 分子名称: | Small-conductance mechanosensitive channel, C-terminal peptide from Small-conductance mechanosensitive channel | 著者 | Li, W, Ge, J, Yang, M. | 登録日 | 2011-10-28 | 公開日 | 2012-10-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.355 Å) | 主引用文献 | Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance Proc.Natl.Acad.Sci.USA, 109, 2012
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1HN2
| CRYSTAL STRUCTURE OF BOVINE OBP COMPLEXED WITH AMINOANTHRACENE | 分子名称: | (3R)-oct-1-en-3-ol, ANTHRACEN-1-YLAMINE, ODORANT-BINDING PROTEIN | 著者 | Vincent, F, Spinelli, S, Tegoni, M, Cambillau, C. | 登録日 | 2000-12-05 | 公開日 | 2001-12-05 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The insect attractant 1-octen-3-ol is the natural ligand of bovine odorant-binding protein. J.Biol.Chem., 276, 2001
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1G85
| CRYSTAL STRUCTURE OF BOVINE ODORANT BINDING PROTEIN COMPLEXED WITH IS NATURAL LIGAND | 分子名称: | (3R)-oct-1-en-3-ol, ODORANT-BINDING PROTEIN | 著者 | Vincent, F, Spinelli, S, Cambillau, C, Tegoni, M. | 登録日 | 2000-11-16 | 公開日 | 2002-06-26 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The insect attractant 1-octen-3-ol is the natural ligand of bovine odorant-binding protein. J.Biol.Chem., 276, 2001
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2H29
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2H2A
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