1YW7
h-MetAP2 complexed with A444148
Summary for 1YW7
Entry DOI | 10.2210/pdb1yw7/pdb |
Related | 1YW8 1YW9 |
Descriptor | Methionine aminopeptidase 2, MANGANESE (II) ION, 5-METHYL-2-[(PHENYLSULFONYL)AMINO]BENZOIC ACID, ... (4 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 41771.20 |
Authors | Park, C.H. (deposition date: 2005-02-17, release date: 2006-02-21, Last modification date: 2011-07-13) |
Primary citation | Sheppard, G.S.,Wang, J.,Kawai, M.,Fidanze, S.D.,BaMaung, N.Y.,Erickson, S.A.,Barnes, D.M.,Tedrow, J.S.,Kolaczkowski, L.,Vasudevan, A.,Park, D.C.,Wang, G.T.,Sanders, W.J.,Mantei, R.A.,Palazzo, F.,Tucker-Garcia, L.,Lou, P.,Zhang, Q.,Park, C.H.,Kim, K.H.,Petros, A.,Olejniczak, E.,Nettesheim, D.,Hajduk, P.,Henkin, J.,Lesniewski, R.,Davidsen, S.K.,Bell, R.L. Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding. J.Med.Chem., 49:3832-3849, 2006 Cited by PubMed: 16789740DOI: 10.1021/jm0601001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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