1UV5

GLYCOGEN SYNTHASE KINASE 3 BETA COMPLEXED WITH 6-BROMOINDIRUBIN-3'-OXIME

Summary for 1UV5

Related1GNG 1H8F 1I09 1J1B 1J1C 1O6K 1O6L 1O9U 1PYX 1Q3D 1Q3W 1Q41 1Q4L
DescriptorGLYCOGEN SYNTHASE KINASE-3 BETA, 6-BROMOINDIRUBIN-3'-OXIME, PHOSPHATE ION, ... (6 entities in total)
Functional Keywordstransferase, kinase, insulin pathway, wnt signaling pathway, transferase serine/threonine-protein kinase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm P49841
Total number of polymer chains1
Total molecular weight40299.14
Authors
Dajani, R.,Pearl, L.H.,Roe, S.M. (deposition date: 2004-01-14, release date: 2004-01-29)
Primary citation
Meijer, L.,Skaltsounis, A.-L.,Magiatis, P.,Polychronopoulous, P.,Knockaert, M.,Leost, M.,Ryan, X.P.,Vonica, C.A.,Brivanlou, A.,Dajani, R.,Crovace, C.,Tarricone, C.,Musacchio, A.,Roe, S.M.,Pearl, L.H.,Greengard, P.
Gsk-3-Selective Inhibitors Derived from Tyrian Purple Indurubins
Chem.Biol., 10:1255-, 2003
PubMed: 14700633 (PDB entries with the same primary citation)
DOI: 10.1016/J.CHEMBIOL.2003.11.010
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers23 3.2% 10.2% 4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02