1GNG

Glycogen synthase kinase-3 beta (GSK3) complex with FRATtide peptide

Summary for 1GNG

• Entry DOI: 10.2210/pdb1gng/pdb
• Related: 1H8F
• Descriptor: GLYCOGEN SYNTHASE KINASE-3 BETA, FRATTIDE, SULFATE ION, ... (5 entities in total)
• Functional Keywords: transferase, protein kinase, gsk3-frattide complex, phosphorylated, active
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm: P49841 Q92837
• Total number of polymer chains: 4
• Total formula weight: 95845.22

Authors

Bax, B.,Carter, P.S.,Lewis, C.,Guy, A.R.,Bridges, A.,Tanner, R.,Pettman, G.,Mannix, C.,Culbert, A.A.,Brown, M.J.B.,Smith, D.G.,Reith, A.D. (deposition date: 2001-10-04, release date: 2002-10-03, Last modification date: 2023-12-13)

• Primary citation: Bax, B.,Carter, P.S.,Lewis, C.,Guy, A.R.,Bridges, A.,Tanner, R.,Pettman, G.,Mannix, C.,Culbert, A.A.,Brown, M.J.B.,Smith, D.G.,Reith, A.D.; The Structure of Phosphorylated Gsk-3Beta Complexed with a Peptide, Frattide, that Inhibits Beta-Catenin Phosphorylation; Structure, 9:1143-, 2001; PubMed: 11738041; DOI: 10.1016/S0969-2126(01)00679-7

Experimental method

X-RAY DIFFRACTION (2.6 Å)