1Q41
GSK-3 Beta complexed with Indirubin-3'-monoxime
Summary for 1Q41
| Entry DOI | 10.2210/pdb1q41/pdb |
| Related | 1PYX 1Q3D 1Q3W 1Q4L |
| Descriptor | GLYCOGEN SYNTHASE KINASE-3 BETA, (Z)-1H,1'H-[2,3']BIINDOLYLIDENE-3,2'-DIONE-3-OXIME (3 entities in total) |
| Functional Keywords | kinase, insulin pathway, indirubin-3'-monoxime, transferase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P49841 |
| Total number of polymer chains | 2 |
| Total formula weight | 94717.50 |
| Authors | Bertrand, J.A.,Thieffine, S.,Vulpetti, A.,Cristiani, C.,Valsasina, B.,Knapp, S.,Kalisz, H.M.,Flocco, M. (deposition date: 2003-08-01, release date: 2003-10-21, Last modification date: 2023-08-16) |
| Primary citation | Bertrand, J.A.,Thieffine, S.,Vulpetti, A.,Cristiani, C.,Valsasina, B.,Knapp, S.,Kalisz, H.M.,Flocco, M. Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors J.Mol.Biol., 333:393-407, 2003 Cited by PubMed: 14529625DOI: 10.1016/j.jmb.2003.08.031 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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