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5EE9
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BU of 5ee9 by Molmil
Complex structure of OSYCHF1 with GMP-PNP
Descriptor: GLYCEROL, MAGNESIUM ION, Obg-like ATPase 1, ...
Authors:Li, X, Chen, Z.
Deposit date:2015-10-22
Release date:2016-02-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:ATP binding by the P-loop NTPase OsYchF1 (an unconventional G protein) contributes to biotic but not abiotic stress responses
Proc.Natl.Acad.Sci.USA, 113, 2016
5EE1
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BU of 5ee1 by Molmil
Crystal structure of OsYchF1 at pH 7.85
Descriptor: Obg-like ATPase 1
Authors:Li, X, Chen, Z.
Deposit date:2015-10-22
Release date:2016-02-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:ATP binding by the P-loop NTPase OsYchF1 (an unconventional G protein) contributes to biotic but not abiotic stress responses
Proc.Natl.Acad.Sci.USA, 113, 2016
5EE3
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BU of 5ee3 by Molmil
COMPLEX STRUCTURE OF OSYCHF1 WITH AMP-PNP
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Li, X, Chen, Z.
Deposit date:2015-10-22
Release date:2016-02-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:ATP binding by the P-loop NTPase OsYchF1 (an unconventional G protein) contributes to biotic but not abiotic stress responses
Proc.Natl.Acad.Sci.USA, 113, 2016
5EE0
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BU of 5ee0 by Molmil
Crystal structure of OsYchF1 at pH 6.5
Descriptor: Obg-like ATPase 1
Authors:Li, X, Chen, Z.
Deposit date:2015-10-22
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:ATP binding by the P-loop NTPase OsYchF1 (an unconventional G protein) contributes to biotic but not abiotic stress responses
Proc.Natl.Acad.Sci.USA, 113, 2016
3NDM
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BU of 3ndm by Molmil
Crystal structure of Rho-Associated Protein Kinase (ROCK1) with a potent isoquinolone derivative
Descriptor: (3S,4R)-N-(7-chloro-1-oxo-1,4-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamide, Rho-Associated Protein Kinase (ROCK1)
Authors:Li, X.
Deposit date:2010-06-07
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 3, aryl substituted pyrrolidines.
Bioorg.Med.Chem.Lett., 20, 2010
4TVQ
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BU of 4tvq by Molmil
CCM3 in complex with CCM2 LD-like motif
Descriptor: Cerebral cavernous malformations 2 protein, Cerebral cavernous malformations 3 protein
Authors:Li, X, Zhang, R, Fisher, O.S, Boggon, T.J.
Deposit date:2014-06-27
Release date:2015-03-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:CCM2-CCM3 interaction stabilizes their protein expression and permits endothelial network formation.
J.Cell Biol., 208, 2015
2LEF
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BU of 2lef by Molmil
LEF1 HMG DOMAIN (FROM MOUSE), COMPLEXED WITH DNA (15BP), NMR, 12 STRUCTURES
Descriptor: DNA (5'-D(*CP*AP*CP*CP*CP*TP*TP*TP*GP*AP*AP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*CP*TP*TP*CP*AP*AP*AP*GP*GP*GP*TP*G)-3'), PROTEIN (LYMPHOID ENHANCER-BINDING FACTOR)
Authors:Li, X, Love, J.J, Case, D.A, Wright, P.E.
Deposit date:1998-10-13
Release date:1998-10-21
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural basis for DNA bending by the architectural transcription factor LEF-1.
Nature, 376, 1995
2FLU
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BU of 2flu by Molmil
Crystal Structure of the Kelch-Neh2 Complex
Descriptor: Kelch-like ECH-associated protein 1, Nrf2
Authors:Li, X, Lo, J, Beamer, L, Hannink, M.
Deposit date:2006-01-06
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling.
Embo J., 25, 2006
5YGI
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BU of 5ygi by Molmil
Crystal structure of human FPPS in complex with an inhibitor THZ93
Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Li, X.
Deposit date:2017-09-23
Release date:2018-09-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.177 Å)
Cite:The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery.
Cell, 175, 2018
3UR1
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BU of 3ur1 by Molmil
The structure of a ternary complex between CheA domains P4 and P5 with CheW and with a truncated fragment of TM14, a chemoreceptor analog from Thermotoga maritima.
Descriptor: Chemotaxis protein CheA, Chemotaxis protein CheW, Methyl-accepting chemotaxis protein
Authors:Li, X, Crane, B.R, Bilwes, A.M.
Deposit date:2011-11-21
Release date:2012-03-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:The structure of native bacterial chemoreceptor arrays
Proc.Natl.Acad.Sci.USA, 2012
7XMX
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BU of 7xmx by Molmil
Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three F61 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, F61 heavy chain, F61 light chain, ...
Authors:Wang, X, Li, X.
Deposit date:2022-04-27
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
7XST
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BU of 7xst by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike glycoprotein in complex with three F61 Fab and three D2 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, D2 heavy chain, D2 light chain, ...
Authors:Wang, X, Li, X.
Deposit date:2022-05-15
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
7XMZ
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BU of 7xmz by Molmil
Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three D2 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, D2 heavy chain, D2 light chain, ...
Authors:Wang, X, Li, X.
Deposit date:2022-04-27
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
7EQH
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BU of 7eqh by Molmil
Crystal structure of Arabidopsis GUN2/HO1 in complex with heme
Descriptor: Heme oxygenase 1, chloroplastic, PROTOPORPHYRIN IX CONTAINING FE
Authors:Li, X, Wang, J, Liu, L.
Deposit date:2021-05-02
Release date:2022-05-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Enzymological and structural characterization of Arabidopsis thaliana heme oxygenase-1.
Febs Open Bio, 12, 2022
7WJQ
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BU of 7wjq by Molmil
Crystal structure of GSDMB in complex with Ipah7.8
Descriptor: Isoform 2 of Gasdermin-B, Probable E3 ubiquitin-protein ligase ipaH7.8
Authors:Li, X, Zhang, H, Yin, H.
Deposit date:2022-01-07
Release date:2023-01-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Insights into the GSDMB-mediated cellular lysis and its targeting by IpaH7.8
Nat Commun, 14, 2023
8J45
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BU of 8j45 by Molmil
Crystal structure of a Pichia pastoris-expressed IsPETase variant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Poly(ethylene terephthalate) hydrolase
Authors:Li, X, He, H.L, Long, X, Niu, D, Huang, J.-W, Chen, C.-C, Guo, R.-T.
Deposit date:2023-04-19
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Complete decomposition of poly(ethylene terephthalate) by crude PET hydrolytic enzyme produced in Pichia pastoris
Chem Eng J, 2023
3NCZ
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BU of 3ncz by Molmil
X-Ray Co-structure of Rho-Associated Protein Kinase (ROCK1) with a potent 2H-isoquinolin-1-one inhibitor
Descriptor: Rho-associated protein kinase 1, cis-4-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)cyclohexanecarboxamide
Authors:Li, X.
Deposit date:2010-06-06
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 2, optimization for blood pressure reduction in spontaneously hypertensive rats.
Bioorg.Med.Chem.Lett., 20, 2010
7T6B
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BU of 7t6b by Molmil
Structure of S1PR2-heterotrimeric G13 signaling complex
Descriptor: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Li, X, Chen, H.
Deposit date:2021-12-13
Release date:2022-04-06
Last modified:2022-06-29
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structure of S1PR2-heterotrimeric G 13 signaling complex.
Sci Adv, 8, 2022
5T17
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BU of 5t17 by Molmil
NMR structure of the E. coli protein NPr, residues 1-85
Descriptor: Phosphocarrier protein NPr
Authors:Wang, G, Li, X, Peterkofsky, A.
Deposit date:2016-08-18
Release date:2016-09-28
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Solution structure of NPr, a bacterial signal-transducing protein that controls the phosphorylation state of the potassium transporter-regulating protein IIA Ntr.
Amino Acids, 35, 2008
7W77
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BU of 7w77 by Molmil
cryo-EM structure of human NaV1.3/beta1/beta2-bulleyaconitineA
Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jiang, D, Li, X.
Deposit date:2021-12-03
Release date:2022-04-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for modulation of human Na V 1.3 by clinical drug and selective antagonist.
Nat Commun, 13, 2022
7W7F
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BU of 7w7f by Molmil
Cryo-EM structure of human NaV1.3/beta1/beta2-ICA121431
Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2,2-diphenyl-~{N}-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]ethanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jiang, D, Li, X.
Deposit date:2021-12-04
Release date:2022-04-06
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural basis for modulation of human Na V 1.3 by clinical drug and selective antagonist.
Nat Commun, 13, 2022
7LIB
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BU of 7lib by Molmil
X-ray crystal structure of a cyclic peptide containing beta-2-microglobulin (63-69) and a gamma-methylornithine turn unit
Descriptor: Cyclic peptide ORD-TYR-LEU-LEU-PHI-TYR-THR-GLU-GMO-LYS-VAL-THR-MVA-THR-VAL-LYS
Authors:Wierzbicki, M, Nowick, J.S, Li, X.
Deposit date:2021-01-26
Release date:2021-08-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:An Improved Turn Structure for Inducing beta-Hairpin Formation in Peptides.
Angew.Chem.Int.Ed.Engl., 60, 2021
7Y9I
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BU of 7y9i by Molmil
Complex structure of AtYchF1 with ppGpp
Descriptor: GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, Obg-like ATPase 1
Authors:Li, X, Chen, Z.
Deposit date:2022-06-24
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Co-crystalization reveals the interaction between AtYchF1 and ppGpp.
Front Mol Biosci, 9, 2022
7YPG
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BU of 7ypg by Molmil
Cryo-EM structure of amyloid fibril formed by tau (297-391)
Descriptor: Isoform Tau-E of Microtubule-associated protein tau
Authors:Zhang, S.Q, Li, X, Liu, C.
Deposit date:2022-08-03
Release date:2022-12-14
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure
Iscience, 25, 2022
6C9U
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BU of 6c9u by Molmil
Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex with antibody fragment (Fab)
Descriptor: 6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Heavy chain of Fab 1B2, ...
Authors:Deis, L.N, Li, X, Mathews, I.I, Khosla, C.
Deposit date:2018-01-28
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module.
J. Am. Chem. Soc., 140, 2018

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