7T6B

Structure of S1PR2-heterotrimeric G13 signaling complex

Summary for 7T6B

• Entry DOI: 10.2210/pdb7t6b/pdb
• EMDB information: 25712
• Descriptor: Guanine nucleotide-binding protein subunit alpha-13, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: s1p, s1pr2, gpcr, membrane protein, cryo-em, signaling protein-immune system complex, signaling protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 158154.27

Authors

Li, X.,Chen, H. (deposition date: 2021-12-13, release date: 2022-04-06, Last modification date: 2022-06-29)

• Primary citation: Chen, H.,Chen, K.,Huang, W.,Staudt, L.M.,Cyster, J.G.,Li, X.; Structure of S1PR2-heterotrimeric G 13 signaling complex.; Sci Adv, 8:eabn0067-eabn0067, 2022; PubMed: 35353559; DOI: 10.1126/sciadv.abn0067

Experimental method

ELECTRON MICROSCOPY (3.19 Å)