7F56
 
 | | DNQX-bound GluK2-1xNeto2 complex, with asymmetric LBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, kainate 2, ... | | 著者 | He, L.L, Gao, Y.W, Li, B, Zhao, Y. | | 登録日 | 2021-06-21 | | 公開日 | 2021-09-29 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Kainate receptor modulation by NETO2.
Nature, 599, 2021
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7F59
 | | DNQX-bound GluK2-1xNeto2 complex | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | 著者 | He, L.L, Gao, Y.W, Li, B, Zhao, Y. | | 登録日 | 2021-06-21 | | 公開日 | 2021-09-29 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Kainate receptor modulation by NETO2.
Nature, 599, 2021
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7F5B
 | | LBD-TMD focused reconstruction of DNQX-bound GluK2-1xNeto2 complex | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | He, L.L, Gao, Y.W, Li, B, Zhao, Y. | | 登録日 | 2021-06-21 | | 公開日 | 2021-09-29 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Kainate receptor modulation by NETO2.
Nature, 599, 2021
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8K4I
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8K5Q
 | | Crystal structure of YajQ STM0435 with c-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), YajQ | | 著者 | Dai, Y, Zhang, M, Wang, W, Li, B. | | 登録日 | 2023-07-23 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | A c-di-GMP binding effector STM0435 modulates flagellar motility and pathogenicity in Salmonella
Virulence, 15, 2024
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3SFV
 | | Crystal structure of the GDP-bound Rab1a S25N mutant in complex with the coiled-coil domain of LidA from Legionella pneumophila | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, LidA protein, substrate of the Dot/Icm system, ... | | 著者 | Yin, K, Lu, D, Zhu, D, Zhang, H, Li, B, Xu, S, Gu, L. | | 登録日 | 2011-06-14 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State
Plos Pathog., 8, 2012
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3TKL
 | | Crystal structure of the GTP-bound Rab1a in complex with the coiled-coil domain of LidA from Legionella pneumophila | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, LidA protein, substrate of the Dot/Icm system, ... | | 著者 | Cheng, W, Yin, K, Lu, D, Li, B, Zhu, D, Chen, Y, Zhang, H, Xu, S, Chai, J, Gu, L. | | 登録日 | 2011-08-27 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.183 Å) | | 主引用文献 | Structural insights into a unique Legionella pneumophila effector LidA recognizing both GDP and GTP bound Rab1 in their active state
Plos Pathog., 8, 2012
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5H3J
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3KUZ
 | | Crystal structure of the ubiquitin like domain of PLXNC1 | | 分子名称: | Plexin-C1, UNKNOWN ATOM OR ION | | 著者 | Wang, H, Li, B, Tempel, W, Tong, Y, Guan, X, Zhong, N, Crombet, L, MacKenzie, F, Buck, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-11-28 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the ubiquitin like domain of PLXNC1
to be published
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5I9J
 | | Structure of the cholesterol and lutein-binding domain of human STARD3 at 1.74A | | 分子名称: | 1,2-ETHANEDIOL, L(+)-TARTARIC ACID, SULFATE ION, ... | | 著者 | Horvath, M.P, Bernstein, P.S, Li, B, George, E.W, Tran, Q.T. | | 登録日 | 2016-02-20 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structure of the lutein-binding domain of human StARD3 at 1.74 angstrom resolution and model of a complex with lutein.
Acta Crystallogr.,Sect.F, 72, 2016
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4PT6
 | | The discobody: an engineered discoidin domain from factor VIII that binds v 3 integrin with antibody-like affinities | | 分子名称: | Coagulation factor VIII | | 著者 | Kym, G, Shi, K, Kamajaya, A, Hamdouche, S, Kostecki, J.S, Wannier, T, Li, B, Nikolovski, P, Mayo, S.L. | | 登録日 | 2014-03-10 | | 公開日 | 2015-04-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The discobody: an engineered discoidin domain from factor VIII that binds v 3 integrin with antibody-like affinities
To be Published
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4REY
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6LK0
 | | Crystal structure of human wild type TRIP13 | | 分子名称: | Pachytene checkpoint protein 2 homolog | | 著者 | Wang, Y, Huang, J, Li, B, Xue, H, Tricot, G, Hu, L, Xu, Z, Sun, X, Chang, S, Gao, L, Tao, Y, Xu, H, Xie, Y, Xiao, W, Yu, D, Kong, Y, Chen, G, Sun, X, Lian, F, Zhang, N, Wu, X, Mao, Z, Zhan, F, Zhu, W, Shi, J. | | 登録日 | 2019-12-17 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Cancer Res., 80, 2020
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4LMQ
 | | Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12 | | 分子名称: | Stromal cell-derived factor 1, hu30D8 Fab heavy chain, hu30D8 Fab light chain | | 著者 | Zhong, Z, Wang, J, Li, B, Xiang, H, Ultsch, M, Coons, M, Wong, T, Chiang, N.Y, Clark, S, Clark, R, Quintana, L, Gribling, P, Suto, E, Barck, K, Corpuz, R, Yao, J, Takkar, R, Lee, W.P, Damico-Beyer, L.A, Carano, R.D, Adams, C, Kelley, R.F, Wang, W, Ferrara, N. | | 登録日 | 2013-07-10 | | 公開日 | 2013-08-14 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.773 Å) | | 主引用文献 | Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12.
Clin.Cancer Res., 19, 2013
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8JBI
 | | SteC 202-375 mutant- C276S | | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Secreted effector kinase SteC | | 著者 | Zhang, M, Dai, Y, Li, B. | | 登録日 | 2023-05-09 | | 公開日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.356 Å) | | 主引用文献 | Salmonella manipulates macrophage cytoskeleton to penetrate gut-vascular barrier and promote dissemination during infection
To Be Published
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7DSV
 | | Structure of a human NHE1-CHP1 complex under pH 6.5 | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Calcineurin B homologous protein 1, Sodium/hydrogen exchanger 1 | | 著者 | Dong, Y, Gao, Y, Li, B, Zhang, X.C, Zhao, Y. | | 登録日 | 2021-01-03 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and mechanism of the human NHE1-CHP1 complex.
Nat Commun, 12, 2021
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7DSW
 | | Structure of a human NHE1-CHP1 complex under pH 7.5 | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Sodium/hydrogen exchanger 1 | | 著者 | Dong, Y, Gao, Y, Li, B, Zhang, X.C, Zhao, Y. | | 登録日 | 2021-01-03 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure and mechanism of the human NHE1-CHP1 complex.
Nat Commun, 12, 2021
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7DSX
 | | Structure of a human NHE1-CHP1 complex under pH 7.5, bound by cariporide | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Calcineurin B homologous protein 1, N-[bis(azanyl)methylidene]-3-methylsulfonyl-4-propan-2-yl-benzamide, ... | | 著者 | Dong, Y, Gao, Y, Li, B, Zhang, X.C, Zhao, Y. | | 登録日 | 2021-01-03 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure and mechanism of the human NHE1-CHP1 complex.
Nat Commun, 12, 2021
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7D7E
 | | Structure of PKD1L3-CTD/PKD2L1 in apo state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Polycystic kidney disease 2-like 1 protein, ... | | 著者 | Su, Q, Chen, M, Li, B, Wang, Y, Jing, D, Zhan, X, Yu, Y, Shi, Y. | | 登録日 | 2020-10-03 | | 公開日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for Ca 2+ activation of the heteromeric PKD1L3/PKD2L1 channel.
Nat Commun, 12, 2021
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7W72
 | | Structure of a human glycosylphosphatidylinositol (GPI) transamidase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GPI transamidase component PIG-S, ... | | 著者 | Zhang, H, Su, J, Li, B, Gao, Y, Zhang, X.C, Zhao, Y. | | 登録日 | 2021-12-02 | | 公開日 | 2022-02-16 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of human glycosylphosphatidylinositol transamidase.
Nat.Struct.Mol.Biol., 29, 2022
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5U8T
 | | Structure of Eukaryotic CMG Helicase at a Replication Fork and Implications | | 分子名称: | Cell division control protein 45, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA replication complex GINS protein PSF1, ... | | 著者 | Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, Li, H, O'Donnell, M.E. | | 登録日 | 2016-12-15 | | 公開日 | 2017-02-08 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2G0D
 | | Nisin cyclase | | 分子名称: | Nisin biosynthesis protein nisC, ZINC ION | | 著者 | Nair, S.K. | | 登録日 | 2006-02-12 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis
Science, 311, 2006
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2G02
 | | Nisin cyclase | | 分子名称: | Nisin biosynthesis protein nisC, ZINC ION | | 著者 | Nair, S.K. | | 登録日 | 2006-02-10 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure and Mechanism of the Lantibiotic Cyclase Involved in Nisin Biosynthesis
Science, 311, 2006
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2H9G
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7KH2
 | | Structure of N-citrylornithine decarboxylase bound with PLP | | 分子名称: | GLYCEROL, N-citrylornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Deng, X, Tomchick, D, Phillips, M, Michael, A. | | 登録日 | 2020-10-19 | | 公開日 | 2020-12-16 | | 最終更新日 | 2021-07-28 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Alternative pathways utilize or circumvent putrescine for biosynthesis of putrescine-containing rhizoferrin.
J.Biol.Chem., 296, 2020
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