4R1O
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4R1Q
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4R1P
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8BV8
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![BU of 8bv8 by Molmil](/molmil-images/mine/8bv8) | Crystal structure of the phage Mu protein Mom inactive mutant S124A | Descriptor: | Methylcarbamoylase mom | Authors: | Silva, R.M.B, Slyvka, A, Lee, Y.J, Guan, C, Lund, S.R, Raleigh, E.A, Skowronek, K, Bochtler, M, Weigele, P.R. | Deposit date: | 2022-12-08 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal structure of the phage Mu protein Mom catalytic mutant S124A To Be Published
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3H94
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![BU of 3h94 by Molmil](/molmil-images/mine/3h94) | Crystal structure of the membrane fusion protein CusB from Escherichia coli | Descriptor: | Cation efflux system protein cusB, SILVER ION | Authors: | Su, C.-C, Yang, F, Long, F, Reyon, D, Routh, M.D, Kuo, D.W, Mokhtari, A.K, Van Ornam, J.D, Rabe, K.L, Hoy, J.A, Lee, Y.J, Rajashankar, K.R, Yu, E.W. | Deposit date: | 2009-04-30 | Release date: | 2009-08-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.84 Å) | Cite: | Crystal structure of the membrane fusion protein CusB from Escherichia coli J.Mol.Biol., 393, 2009
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3OOC
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![BU of 3ooc by Molmil](/molmil-images/mine/3ooc) | Crystal structure of the membrane fusion protein CusB from Escherichia coli | Descriptor: | Cation efflux system protein cusB | Authors: | Su, C.-C, Yang, F, Long, F, Reyon, D, Routh, M.D, Kuo, D.W, Mokhtari, A.K, Van Ornam, J.D, Rabe, K.L, Hoy, J.A, Lee, Y.J, Rajashankar, K.R, Yu, E.W. | Deposit date: | 2010-08-30 | Release date: | 2010-12-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.404 Å) | Cite: | Crystal structure of the membrane fusion protein CusB from Escherichia coli. J.Mol.Biol., 393, 2009
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5K1P
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5K1X
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5Y7W
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![BU of 5y7w by Molmil](/molmil-images/mine/5y7w) | Crystal structure of the Nco-A1 PAS-B domain with YL-2 | Descriptor: | Nuclear receptor coactivator 1, YL-2 peptide | Authors: | Lee, Y.J, Yoon, H.S, Lee, J.H, Bae, J.H, Song, J.Y, Lim, H.S. | Deposit date: | 2017-08-18 | Release date: | 2017-11-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Targeted Inhibition of the NCOA1/STAT6 Protein-Protein Interaction J. Am. Chem. Soc., 139, 2017
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5GGR
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![BU of 5ggr by Molmil](/molmil-images/mine/5ggr) | PD-1 in complex with nivolumab Fab | Descriptor: | Programmed cell death protein 1, heavy chain, light chain | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGQ
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![BU of 5ggq by Molmil](/molmil-images/mine/5ggq) | Crystal structure of Nivolumab Fab fragment | Descriptor: | nivolumab heavy chain, nivolumab light chain | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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4ZRM
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4ZRN
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5GGU
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![BU of 5ggu by Molmil](/molmil-images/mine/5ggu) | Crystal structure of tremelimumab Fab | Descriptor: | heavy chain, light chain | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (2.292 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGS
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![BU of 5ggs by Molmil](/molmil-images/mine/5ggs) | PD-1 in complex with pembrolizumab Fab | Descriptor: | Programmed cell death protein 1, heavy chain, light chain | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGV
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![BU of 5ggv by Molmil](/molmil-images/mine/5ggv) | CTLA-4 in complex with tremelimumab Fab | Descriptor: | Cytotoxic T-lymphocyte protein 4, heavy chain, light chain | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2016-11-16 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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5GGT
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![BU of 5ggt by Molmil](/molmil-images/mine/5ggt) | PD-L1 in complex with BMS-936559 Fab | Descriptor: | IGK@ protein, IgG H chain, Programmed cell death 1 ligand 1 | Authors: | Heo, Y.S. | Deposit date: | 2016-06-16 | Release date: | 2016-11-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
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4S3G
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![BU of 4s3g by Molmil](/molmil-images/mine/4s3g) | Structure of the F249X mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, ACETATE ION | Authors: | He, T, Gershenson, A, Eyles, S.J, Gao, J, Roberts, M.F. | Deposit date: | 2015-01-26 | Release date: | 2015-07-01 | Last modified: | 2015-08-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Fluorinated Aromatic Amino Acids Distinguish Cation-pi Interactions from Membrane Insertion. J.Biol.Chem., 290, 2015
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4RV3
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![BU of 4rv3 by Molmil](/molmil-images/mine/4rv3) | Crystal structure of a pentafluoro-Phe incorporated Phosphatidylinositol-specific phospholipase C (H258X)from Staphylococcus aureus | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, ACETATE ION | Authors: | He, T, Gershenson, A, Eyles, S.J, Gao, J, Roberts, M.F. | Deposit date: | 2014-11-24 | Release date: | 2015-07-01 | Last modified: | 2018-08-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Fluorinated Aromatic Amino Acids Distinguish Cation-pi Interactions from Membrane Insertion. J.Biol.Chem., 290, 2015
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2C83
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![BU of 2c83 by Molmil](/molmil-images/mine/2c83) | CRYSTAL STRUCTURE OF THE SIALYLTRANSFERASE PM0188 | Descriptor: | HYPOTHETICAL PROTEIN PM0188 | Authors: | Kim, D.U, Cho, H.S. | Deposit date: | 2005-12-01 | Release date: | 2007-03-27 | Last modified: | 2019-10-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural analysis of sialyltransferase PM0188 from Pasteurella multocida complexed with donor analogue and acceptor sugar. Bmb Rep, 41, 2008
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2C84
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![BU of 2c84 by Molmil](/molmil-images/mine/2c84) | CRYSTAL STRUCTURE OF THE SIALYLTRANSFERASE PM0188 WITH CMP | Descriptor: | ALPHA-2,3/2,6-SIALYLTRANSFERASE/SIALIDASE, CYTIDINE-5'-MONOPHOSPHATE | Authors: | Kim, D.U, Cho, H.S. | Deposit date: | 2005-12-01 | Release date: | 2007-03-27 | Last modified: | 2019-10-09 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structural analysis of sialyltransferase PM0188 from Pasteurella multocida complexed with donor analogue and acceptor sugar. Bmb Rep, 41, 2008
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5T9U
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![BU of 5t9u by Molmil](/molmil-images/mine/5t9u) | Discovery of a Potent Cyclophilin Inhibitor (Compound 3) based on Structural Simplification of Sanglifehrin A | Descriptor: | 3-[(3-hydroxyphenyl)methyl]-10,12-dimethoxy-9,11-dimethyl-6-(propan-2-yl)-19-oxa-1,4,7,25-tetraazabicyclo[19.3.1]pentacosa-13,15-diene-2,5,8,20-tetrone, Peptidyl-prolyl cis-trans isomerase A | Authors: | Appleby, T.C, Steadman, V, Pettit, S, Schmitz, U, Mackman, R.L, Schultz, B. | Deposit date: | 2016-09-09 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A. J. Med. Chem., 60, 2017
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5T9Z
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![BU of 5t9z by Molmil](/molmil-images/mine/5t9z) | Discovery of a Potent Cyclophilin Inhibitor (Compound 6) based on Structural Simplification of Sanglifehrin A | Descriptor: | 11-[(3-hydroxyphenyl)methyl]-18-methoxy-17-methyl-14-(propan-2-yl)-3-oxa-9,12,15,28-tetraazatricyclo[21.3.1.1~5,9~]octacosa-1(27),21,23,25-tetraene-4,10,13,16-tetrone, Peptidyl-prolyl cis-trans isomerase A | Authors: | Appleby, T.C, Steadman, V, Pettit, S, Schmitz, U, Mackman, R.L, Schultz, B. | Deposit date: | 2016-09-09 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A. J. Med. Chem., 60, 2017
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5TA2
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![BU of 5ta2 by Molmil](/molmil-images/mine/5ta2) | Discovery of a Potent Cyclophilin Inhibitor (Compound 7) based on Structural Simplification of Sanglifehrin A | Descriptor: | 11-[(3-hydroxyphenyl)methyl]-18-methoxy-2,17-dimethyl-14-(propan-2-yl)-3-oxa-9,12,15,28-tetraazatricyclo[21.3.1.1~5,9~]octacosa-1(27),21,23,25-tetraene-4,10,13,16-tetrone, Peptidyl-prolyl cis-trans isomerase A | Authors: | Appleby, T.C, Steadman, V, Pettit, S, Schmitz, U, Mackman, R.L, Schultz, B. | Deposit date: | 2016-09-09 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A. J. Med. Chem., 60, 2017
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5TA4
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![BU of 5ta4 by Molmil](/molmil-images/mine/5ta4) | Discovery of a Potent Cyclophilin Inhibitor (Compound 8) based on Structural Simplification of Sanglifehrin A | Descriptor: | 18-methoxy-2,11,17-trimethyl-14-(propan-2-yl)-3-oxa-9,12,15,28-tetraazatricyclo[21.3.1.1~5,9~]octacosa-1(27),21,23,25-tetraene-4,10,13,16-tetrone, Peptidyl-prolyl cis-trans isomerase A, SULFATE ION | Authors: | Appleby, T.C, Steadman, V, Pettit, S, Schmitz, U, Mackman, R.L, Schultz, B. | Deposit date: | 2016-09-09 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A. J. Med. Chem., 60, 2017
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