4RV3
Crystal structure of a pentafluoro-Phe incorporated Phosphatidylinositol-specific phospholipase C (H258X)from Staphylococcus aureus
Summary for 4RV3
| Entry DOI | 10.2210/pdb4rv3/pdb |
| Related | 3V16 |
| Descriptor | 1-phosphatidylinositol phosphodiesterase, ACETATE ION, 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, ... (4 entities in total) |
| Functional Keywords | cation-pi, tim barrel, encoded unnatural amino acid phospholipase, lyase |
| Biological source | Staphylococcus aureus |
| Total number of polymer chains | 1 |
| Total formula weight | 34535.26 |
| Authors | He, T.,Gershenson, A.,Eyles, S.J.,Gao, J.,Roberts, M.F. (deposition date: 2014-11-24, release date: 2015-07-01, Last modification date: 2018-08-29) |
| Primary citation | He, T.,Gershenson, A.,Eyles, S.J.,Lee, Y.J.,Liu, W.R.,Wang, J.,Gao, J.,Roberts, M.F. Fluorinated Aromatic Amino Acids Distinguish Cation-pi Interactions from Membrane Insertion. J.Biol.Chem., 290:19334-19342, 2015 Cited by PubMed: 26092728DOI: 10.1074/jbc.M115.668343 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report
