7EYC
 
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3CNK
 | | Crystal Structure of the dimerization domain of human filamin A | | 分子名称: | Filamin-A, SULFATE ION | | 著者 | Lee, B.J, Seo, M.D, Seok, S.H, Lee, S.J, Kwon, A.R, Im, H. | | 登録日 | 2008-03-26 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structure of the dimerization domain of human filamin A
Proteins, 75, 2008
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6YD0
 | | XFEL structure of the Soluble methane monooxygenase hydroxylase and regulatory subunit complex, from Methylosinus trichosporium OB3b, diferric state | | 分子名称: | FE (III) ION, GLYCEROL, Methane monooxygenase, ... | | 著者 | Srinivas, V, Hogbom, M. | | 登録日 | 2020-03-19 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States.
J. Am. Chem. Soc., 142, 2020
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6YDU
 | | XFEL structure of the Soluble methane monooxygenase hydroxylase and regulatory subunit complex, from Methylosinus trichosporium OB3b, reoxidized diferric state, 10s O2 exposure. | | 分子名称: | FE (III) ION, GLYCEROL, Methane monooxygenase, ... | | 著者 | Srinivas, V, Hogbom, M. | | 登録日 | 2020-03-21 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States.
J. Am. Chem. Soc., 142, 2020
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6YDI
 | | XFEL structure of the Soluble methane monooxygenase hydroxylase and regulatory subunit complex, from Methylosinus trichosporium OB3b, diferrous state | | 分子名称: | FE (II) ION, GLYCEROL, Methane monooxygenase, ... | | 著者 | Srinivas, V, Hogbom, M. | | 登録日 | 2020-03-20 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States.
J. Am. Chem. Soc., 142, 2020
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6YY3
 | | XFEL structure of the Soluble methane monooxygenase hydroxylase and regulatory subunit complex, from Methylosinus trichosporium OB3b, t=0 diferrous state prior to oxygen activation | | 分子名称: | FE (II) ION, GLYCEROL, Methane monooxygenase, ... | | 著者 | Srinivas, V, Hogbom, M. | | 登録日 | 2020-05-04 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States.
J. Am. Chem. Soc., 142, 2020
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5WHD
 | | Crystal structure of KRas G12V/D38P, bound to GDP | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Shim, S.Y, McGee, J.H, Lee, S.-J, Verdine, G.L. | | 登録日 | 2017-07-16 | | 公開日 | 2018-01-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | | 主引用文献 | Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
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5WPM
 | | KRas G12V, bound to GppNHp and miniprotein 225-11(A30R) | | 分子名称: | GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Lee, S.-J, Shim, S.Y, McGee, J.H, Verdine, G.L. | | 登録日 | 2017-08-05 | | 公開日 | 2018-01-03 | | 最終更新日 | 2018-03-14 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
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6W0M
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6W13
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6W0R
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5DMV
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5DNJ
 | | Mouse Polo-box domain and Peptide analog 702 | | 分子名称: | Serine/threonine-protein kinase PLK1, peptide 707-56A-SER-TPO-NH2 | | 著者 | Namgoong, S, Han, Y.H. | | 登録日 | 2015-09-10 | | 公開日 | 2016-02-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
Sci Rep, 5, 2015
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5DMS
 | | Mouse Polo-box domain and Emi2 (169-177) | | 分子名称: | F-box only protein 43, Serine/threonine-protein kinase PLK1 | | 著者 | Namgoong, S. | | 登録日 | 2015-09-09 | | 公開日 | 2015-10-28 | | 実験手法 | X-RAY DIFFRACTION (1.89999 Å) | | 主引用文献 | Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
Sci Rep, 5, 2015
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4RSS
 | | Crystal structure of tyrosine-protein kinase SYK with an inhibitor | | 分子名称: | 1-[(3-methyl-1-{2-[(1,2,3-trimethyl-1H-indol-5-yl)amino]pyrimidin-4-yl}-1H-pyrazol-4-yl)methyl]azetidin-3-ol, Tyrosine-protein kinase SYK | | 著者 | Lee, B.I, Lee, S.J, Choi, J.-S. | | 登録日 | 2014-11-11 | | 公開日 | 2015-10-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Highly potent and selective pyrazolylpyrimidines as Syk kinase inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
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3QPH
 | | The three-dimensional structure of TrmB, a global transcriptional regulator of the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose | | 分子名称: | ACETATE ION, GLYCEROL, TrmB, ... | | 著者 | Krug, M, Lee, S.-J, Boos, W, Welte, W, Diederichs, K. | | 登録日 | 2011-02-13 | | 公開日 | 2012-05-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.992 Å) | | 主引用文献 | The three-dimensional structure of TrmB, a transcriptional regulator of dual function in the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose.
Protein Sci., 22, 2013
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7X1K
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6IRP
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6M84
 | | Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2 | | 分子名称: | ATP-sensitive inward rectifier potassium channel 12, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ... | | 著者 | Lee, S.-J, Ren, F, Yuan, P, Nichols, C.G. | | 登録日 | 2018-08-21 | | 公開日 | 2019-09-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels.
J.Gen.Physiol., 152, 2020
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6M85
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6OQA
 | | Crystal structure of CEP250 bound to FKBP12 in the presence of FK506-like novel natural product | | 分子名称: | (3R,4E,7E,10R,11S,12R,13S,16R,17R,24aS)-11,17-dihydroxy-10,12,16-trimethyl-3-[(2R)-1-phenylbutan-2-yl]-6,9,10,11,12,13,14,15,16,17,22,23,24,24a-tetradecahydro-3H-13,17-epoxypyrido[2,1-c][1,4]oxazacyclohenicosine-1,18,19(21H)-trione, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | | 著者 | Lee, S.-J, Shigdel, U.K, Townson, S.A, Verdine, G.L. | | 登録日 | 2019-04-26 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5WHA
 | | KRas G12V, bound to GDP and miniprotein 225-11 | | 分子名称: | CALCIUM ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Shim, S.Y, McGee, J.H, Lee, S.-J, Verdine, G.L. | | 登録日 | 2017-07-16 | | 公開日 | 2018-01-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
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5WHB
 | | KRas G12V, bound to GDP and miniprotein 225-11(A30R) | | 分子名称: | CALCIUM ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Shim, S.Y, McGee, J.H, Lee, S.-J, Verdine, G.L. | | 登録日 | 2017-07-16 | | 公開日 | 2018-01-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
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5WLB
 | | KRas G12V, bound to GppNHp and miniprotein 225-15a/b | | 分子名称: | 225-15 a, 225-15 b, GTPase KRas, ... | | 著者 | Shim, S.Y, McGee, J.H, Lee, S.-J, Verdine, G.L. | | 登録日 | 2017-07-26 | | 公開日 | 2018-01-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
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5WPL
 | | KRas G12V, bound to GppNHp and miniprotein 225-11 | | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Lee, S.-J, Shim, S.Y, McGee, J.H, Verdine, G.L. | | 登録日 | 2017-08-05 | | 公開日 | 2018-01-03 | | 最終更新日 | 2018-03-14 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
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