5WHD

Crystal structure of KRas G12V/D38P, bound to GDP

Summary for 5WHD

Entry DOI	10.2210/pdb5whd/pdb
Related	5KLJ
Descriptor	GTPase KRas, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywords	open conformation of ras, gtp binding protein, protein binding
Biological source	Homo sapiens (Human)
Cellular location	Cell membrane ; Lipid-anchor ; Cytoplasmic side : P01116
Total number of polymer chains	4
Total formula weight	78319.20
Authors	Shim, S.Y.,McGee, J.H.,Lee, S.-J.,Verdine, G.L. (deposition date: 2017-07-16, release date: 2018-01-03, Last modification date: 2023-10-04)
Primary citation	McGee, J.H.,Shim, S.Y.,Lee, S.J.,Swanson, P.K.,Jiang, S.Y.,Durney, M.A.,Verdine, G.L. Exceptionally high-affinity Ras binders that remodel its effector domain. J. Biol. Chem., 293:3265-3280, 2018 Cited by PubMed: 29282294 DOI: 10.1074/jbc.M117.816348 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.641 Å)

Structure validation