5WHD

Crystal structure of KRas G12V/D38P, bound to GDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	GTPase KRas	polymer	170	19136.6	4	UniProt (P01116) Pfam (PF00071) In PDB	Homo sapiens (Human)	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2	A, B, C, D	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	4	Chemie (GDP)
3		water	water		18.0	290	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 166 (UniProt: P01116)

PDB	External Database	Details
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag
Val 12	Gly 12	engineered mutation
Pro 38	Asp 38	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	76546.4
Non-Polymers*	Number of molecules	4
	Total formula weight	1772.8
All*	Total formula weight	78319.2

*Water molecules are not included.