6W13
Human 8-oxoguanine glycosylase interrogating fully intrahelical oxoG lesion DNA
Summary for 6W13
Entry DOI | 10.2210/pdb6w13/pdb |
Descriptor | N-glycosylase/DNA lyase, DNA (5'-D(P*CP*AP*(8OG)P*GP*TP*CP*T)-3'), DNA (5'-D(P*AP*CP*CP*TP*GP*G)-3'), ... (7 entities in total) |
Functional Keywords | hogg1, 8-oxog, encounter complex, interrogation complex, dna binding protein, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 39974.53 |
Authors | Shigdel, U.,Verdine, G. (deposition date: 2020-03-03, release date: 2020-09-23, Last modification date: 2023-10-18) |
Primary citation | Shigdel, U.K.,Ovchinnikov, V.,Lee, S.J.,Shih, J.A.,Karplus, M.,Nam, K.,Verdine, G.L. The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. Nat Commun, 11:4437-4437, 2020 Cited by PubMed: 32895378DOI: 10.1038/s41467-020-18290-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.38 Å) |
Structure validation
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