6W13
Human 8-oxoguanine glycosylase interrogating fully intrahelical oxoG lesion DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | N-glycosylase/DNA lyase | polymer | 317 | 35670.4 | 1 | UniProt (O15527) Pfam (PF07934) Pfam (PF00730) | Homo sapiens (Human) | |
| 2 | B (B) | DNA (5'-D(P*CP*AP*(8OG)P*GP*TP*CP*T)-3') | polymer | 7 | 2129.4 | 1 | Homo sapiens | ||
| 3 | C (C) | DNA (5'-D(P*AP*CP*CP*TP*GP*G)-3') | polymer | 6 | 1809.2 | 1 | Homo sapiens | ||
| 4 | D, E, F, G (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | H, I (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 6 | J (B) | 2-(2-ethoxyethoxy)ethanethiol | non-polymer | 150.2 | 1 | Chemie (S5Y) | |||
| 7 | K, L (A, B) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A: 12 - 325 (UniProt: O15527)
| PDB | External Database | Details |
|---|---|---|
| Gly 9 | - | expression tag |
| Ser 10 | - | expression tag |
| Glu 11 | - | expression tag |
| Gln 122 | Glu 122 | engineered mutation |
| Cys 207 | Tyr 207 | engineered mutation |
| Trp 253 | Cys 253 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 39609.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 365.5 | |
| All* | Total formula weight | 39974.5 |
