5WLB
KRas G12V, bound to GppNHp and miniprotein 225-15a/b
Summary for 5WLB
Entry DOI | 10.2210/pdb5wlb/pdb |
Related | 5WHA |
Descriptor | GTPase KRas, 225-15 a, 225-15 b, ... (8 entities in total) |
Functional Keywords | ras binders, gtp binding protein, protein binding |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side : P01116 |
Total number of polymer chains | 6 |
Total formula weight | 55315.50 |
Authors | Shim, S.Y.,McGee, J.H.,Lee, S.-J.,Verdine, G.L. (deposition date: 2017-07-26, release date: 2018-01-03, Last modification date: 2023-10-04) |
Primary citation | McGee, J.H.,Shim, S.Y.,Lee, S.J.,Swanson, P.K.,Jiang, S.Y.,Durney, M.A.,Verdine, G.L. Exceptionally high-affinity Ras binders that remodel its effector domain. J. Biol. Chem., 293:3265-3280, 2018 Cited by PubMed: 29282294DOI: 10.1074/jbc.M117.816348 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
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