5WLB
KRas G12V, bound to GppNHp and miniprotein 225-15a/b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | GTPase KRas | polymer | 166 | 18926.4 | 2 | UniProt (P01116) Pfam (PF00071) In PDB | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B, E | 225-15 a | polymer | 34 | 4181.5 | 2 | synthetic construct | ||
| 3 | C, F | 225-15 b | polymer | 34 | 3810.2 | 2 | synthetic construct | ||
| 4 | A, D | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) | |||
| 5 | A, D | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 7 | C | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 8 | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 166 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Val 12 | Gly 12 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 53836.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1479.4 | |
| All* | Total formula weight | 55315.5 |
