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2OOB
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BU of 2oob by Molmil
crystal structure of the UBA domain from Cbl-b ubiquitin ligase in complex with ubiquitin
Descriptor: E3 ubiquitin-protein ligase CBL-B, Ubiquitin
Authors:Kozlov, G, Gehring, K.
Deposit date:2007-01-25
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b.
Mol.Cell, 27, 2007
1JCU
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BU of 1jcu by Molmil
Solution Structure of MTH1692 Protein from Methanobacterium thermoautotrophicum
Descriptor: conserved protein MTH1692
Authors:Kozlov, G, Ekiel, I, Gehring, K.
Deposit date:2001-06-11
Release date:2002-07-24
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:An NMR approach to structural proteomics.
Proc.Natl.Acad.Sci.USA, 99, 2002
1GH9
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BU of 1gh9 by Molmil
SOLUTION STRUCTURE OF A 8.3 KDA PROTEIN (GENE MTH1184) FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
Descriptor: 8.3 KDA PROTEIN (GENE MTH1184)
Authors:Kozlov, G, Ekiel, I, Gehring, K, Northeast Structural Genomics Consortium (NESG)
Deposit date:2000-11-30
Release date:2000-12-11
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural proteomics of an archaeon.
Nat.Struct.Biol., 7, 2000
5TDC
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BU of 5tdc by Molmil
Crystal structure of the human UBR-box domain from UBR1 in complex with monomethylated arginine peptide.
Descriptor: E3 ubiquitin-protein ligase UBR1, NMM-ILE-PHE-SER peptide, SULFATE ION, ...
Authors:Kozlov, G, Munoz-Escobar, J, Matta-Camacho, E, Gehring, K.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.607 Å)
Cite:Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Structure, 25, 2017
5TSR
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BU of 5tsr by Molmil
Crystal structure of PRL-3 phosphatase in complex with the Bateman domain of CNNM3 magnesium transporter
Descriptor: Metal transporter CNNM3, Protein tyrosine phosphatase type IVA 3
Authors:Kozlov, G, Zhang, H, Gehring, K.
Deposit date:2016-10-31
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.188 Å)
Cite:PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3.
Sci Rep, 7, 2017
4NWY
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BU of 4nwy by Molmil
Crystal structure of the b' domain of human protein disulfide isomerase-like protein of the testis (PDILT)
Descriptor: FORMIC ACID, Protein disulfide-isomerase-like protein of the testis
Authors:Bastos-Aristizabal, S, Kozlov, G, Gehring, K.
Deposit date:2013-12-07
Release date:2014-04-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the substrate-binding b' domain of the Protein disulfide isomerase-like protein of the testis.
Sci Rep, 4, 2014
5K23
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BU of 5k23 by Molmil
Crystal structure of the complex between human phosphatase PRL-2 in the oxidized state with the Bateman domain of human magnesium transporter CNNM3
Descriptor: Metal transporter CNNM3, Protein tyrosine phosphatase type IVA 2
Authors:Gulerez, I, Kozlov, G, Gehring, K.
Deposit date:2016-05-18
Release date:2016-10-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3.
Sci Rep, 7, 2017
4F02
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BU of 4f02 by Molmil
Crystal structure of the PABP-binding site of eIF4G in complex with RRM1-2 of PABP and poly(A)
Descriptor: Eukaryotic translation initiation factor 4 gamma 1, Polyadenylate-binding protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
Authors:Safaee, N, Kozlov, G, Gehring, K.B.
Deposit date:2012-05-03
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
5V44
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BU of 5v44 by Molmil
Crystal structure of the SR1 domain of human sacsin
Descriptor: GLYCEROL, Sacsin
Authors:Menade, M, Kozlov, G, Gehring, K.
Deposit date:2017-03-08
Release date:2017-05-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
J. Biol. Chem., 293, 2018
8CT8
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BU of 8ct8 by Molmil
Crystal structure of Drosophila melanogaster PRL/CBS-pair domain complex
Descriptor: IODIDE ION, PRL-1 phosphatase, Unextended protein
Authors:Fakih, R, Goldstein, R.H, Kozlov, G, Gehring, K.
Deposit date:2022-05-13
Release date:2023-03-01
Last modified:2023-04-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver.
J.Biol.Chem., 299, 2023
4EF0
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BU of 4ef0 by Molmil
Crystal Structure of the first catalytic domain of protein disulfide isomerase P5
Descriptor: Protein disulfide-isomerase A6
Authors:Vinaik, R, Kozlov, G, Gehring, K.
Deposit date:2012-03-28
Release date:2013-04-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of the first catalytic domain of protein disulfide isomerase P5
To be Published
4K95
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BU of 4k95 by Molmil
Crystal Structure of Parkin
Descriptor: E3 ubiquitin-protein ligase parkin, ZINC ION
Authors:Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K.
Deposit date:2013-04-19
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6.499 Å)
Cite:Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013
1NMR
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BU of 1nmr by Molmil
Solution Structure of C-terminal Domain from Trypanosoma cruzi Poly(A)-Binding Protein
Descriptor: poly(A)-binding protein
Authors:Siddiqui, N, Kozlov, G, D'Orso, I, Trempe, J.F, Frasch, A.C.C, Gehring, K.
Deposit date:2003-01-10
Release date:2003-09-09
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution Structure of the C-terminal Domain from poly(A)-binding protein in Trypanosoma cruzi: A vegetal PABC domain
Protein Sci., 12, 2003
7M1U
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BU of 7m1u by Molmil
Crystal structure of an archaeal CNNM, MtCorB, R235L mutant with C-terminal deletion
Descriptor: Hemolysin, contains CBS domains
Authors:Chen, Y.S, Kozlov, G, Gehring, K.
Deposit date:2021-03-15
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of an archaeal CorB magnesium transporter.
Nat Commun, 12, 2021
7M1T
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BU of 7m1t by Molmil
Crystal structure of an archaeal CNNM, MtCorB, with C-terminal deletion in complex with Mg2+-ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Hemolysin, contains CBS domains, ...
Authors:Chen, Y.S, Kozlov, G, Gehring, K.
Deposit date:2021-03-15
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Crystal structure of an archaeal CorB magnesium transporter.
Nat Commun, 12, 2021
3PKN
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BU of 3pkn by Molmil
Crystal structure of MLLE domain of poly(A) binding protein in complex with PAM2 motif of La-related protein 4 (LARP4)
Descriptor: IODIDE ION, La-related protein 4, Polyadenylate-binding protein 1, ...
Authors:Xie, J, Kozlov, G, Gehring, K.
Deposit date:2010-11-11
Release date:2011-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability.
Mol.Cell.Biol., 31, 2011
5K35
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BU of 5k35 by Molmil
Structure of the Legionella effector, AnkB, in complex with human Skp1
Descriptor: Ankyrin-repeat protein B, S-phase kinase-associated protein 1
Authors:Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2016-05-19
Release date:2017-01-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System.
Structure, 25, 2017
5K34
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BU of 5k34 by Molmil
Structure of the ankyrin domain of AnkB from Legionella Pneumophila
Descriptor: Ankyrin-repeat protein B, GLYCEROL, SULFATE ION
Authors:Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2016-05-19
Release date:2017-01-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System.
Structure, 25, 2017
5K25
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BU of 5k25 by Molmil
Crystal structure of human phosphatase PRL-2 in complex with the ADP-bound Bateman domain of human magnesium transporter CNNM3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Metal transporter CNNM3, Protein tyrosine phosphatase type IVA 2
Authors:Gulerez, I, Kozlov, G, Gehring, K.
Deposit date:2016-05-18
Release date:2016-10-12
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3.
Sci Rep, 7, 2017
3PT3
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BU of 3pt3 by Molmil
Crystal structure of the C-terminal lobe of the human UBR5 HECT domain
Descriptor: E3 ubiquitin-protein ligase UBR5
Authors:Matta-Camacho, E, Kozlov, G, Menade, M, Gehring, K.
Deposit date:2010-12-02
Release date:2012-01-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure of the HECT C-lobe of the UBR5 E3 ubiquitin ligase.
Acta Crystallogr.,Sect.F, 68, 2012
3IQL
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BU of 3iql by Molmil
Crystal structure of the rat endophilin-A1 SH3 domain
Descriptor: CHLORIDE ION, Endophilin-A1
Authors:Trempe, J.F, Kozlov, G, Camacho, E.M, Gehring, K.
Deposit date:2009-08-20
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.
Mol.Cell, 36, 2009
5VMD
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BU of 5vmd by Molmil
Crystal structure of UBR-box from UBR6 in a domain-swapping conformation
Descriptor: 1,2-ETHANEDIOL, F-box only protein 11, ZINC ION
Authors:Munoz-Escobar, J, Kozlov, G, Gehring, K.
Deposit date:2017-04-27
Release date:2017-07-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Crystal structure of the UBR-box from UBR6/FBXO11 reveals domain swapping mediated by zinc binding.
Protein Sci., 26, 2017
5TDA
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BU of 5tda by Molmil
Crystal structure of the UBR-box domain from UBR2 in complex with RLWS N-degron
Descriptor: ARG-LEU-TRP-SER peptide, E3 ubiquitin-protein ligase UBR2, ZINC ION
Authors:Munoz-Escobar, J, Kozlov, G, Gehring, K.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (0.79 Å)
Cite:Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Structure, 25, 2017
2K18
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BU of 2k18 by Molmil
Solution structure of bb' domains of human protein disulfide isomerase
Descriptor: Protein disulfide-isomerase
Authors:Denisov, A.Y, Maattanen, P, Dabrowski, C, Kozlov, G, Thomas, D.Y, Gehring, K.
Deposit date:2008-02-22
Release date:2008-04-29
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the bb' domains of human protein disulfide isomerase.
Febs J., 276, 2009
1RYJ
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BU of 1ryj by Molmil
Solution NMR Structure of Protein Mth1743 from Methanobacterium thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH1743_1_70; Northeast Structural Genomics Consortium Target TT526.
Descriptor: unknown
Authors:Yee, A, Chang, X, Pineda-Lucena, A, Wu, B, Semesi, A, Le, B, Ramelot, T, Lee, G.M, Bhattacharyya, S, Gutierrez, P, Denisov, A, Lee, C.H, Cort, J.R, Kozlov, G, Liao, J, Finak, G, Chen, L, Wishart, D, Lee, W, McIntosh, L.P, Gehring, K, Kennedy, M.A, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
Deposit date:2003-12-22
Release date:2004-02-24
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:AN NMR APPROACH TO STRUCTURAL PROTEOMICS
Proc.Natl.Acad.Sci.USA, 99, 2002

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